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After re\u2010induction, patients received rituximab maintenance regimen consisting of a single 375\u2009mg\/m<jats:sup>2<\/jats:sup> dose administered at 4\u2009month intervals, with a maximum of 6 doses. Primary endpoints were duration of response and safety. Sixteen patients: ITP (9), autoimmune haemolytic anaemia (2), and Evans syndrome (5) received rituximab maintenance. 15\/16 achieved complete response (CR); 8\/15 CR\u2009+\u20091 partial reponse remain in remission. Median response: 43\u2009months; estimated 5\u2010year relapse\u2010free &gt;50%. Three developed hypogammaglobulinemia. Rituximab maintenance led to prolonged remissions in patients with autoimmune cytopenias who had previously responded to rituximab induction.<\/jats:p>","DOI":"10.1111\/bjh.18814","type":"journal-article","created":{"date-parts":[[2023,4,22]],"date-time":"2023-04-22T11:38:35Z","timestamp":1682163515000},"page":"153-158","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Maintenence rituximab following induction in autoimmune cytopenias"],"prefix":"10.1111","volume":"202","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4162-033X","authenticated-orcid":false,"given":"Manoj P.","family":"Rai","sequence":"first","affiliation":[{"name":"Division of Hematology\u2010Oncology Oregon Health and Science University  Portland Oregon USA"},{"name":"Divisions of Hematology\/Oncology and Pediatric Hematology\u2010Oncology Weill Cornell Medical College  New York New\u00a0York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8340-6027","authenticated-orcid":false,"given":"Eun\u2010Ju","family":"Lee","sequence":"additional","affiliation":[{"name":"Divisions of Hematology\/Oncology and Pediatric Hematology\u2010Oncology Weill Cornell Medical College  New York New\u00a0York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2884-9247","authenticated-orcid":false,"given":"James B.","family":"Bussel","sequence":"additional","affiliation":[{"name":"Divisions of Hematology\/Oncology and Pediatric Hematology\u2010Oncology Weill Cornell Medical College  New York New\u00a0York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,4,22]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-07-162503"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(96)12118-8"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra010501"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1054\/blre.2001.0173"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1054\/blre.2001.0172"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1951.03810010058005"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2019.218883"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2004.04889.x"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-11-393975"},{"issue":"1","key":"e_1_2_12_11_1","first-page":"31","article-title":"Idiopathic thrombocytopenic purpura associated with mantle cell lymphoma showing an increase in the platelet count receiving anti\u2010CD20 antibody rituximab","volume":"44","author":"Kawachi Y","year":"2003","journal-title":"Rinsho Ketsueki"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/ejh.12839"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.21512"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2015.125344"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)62175-7"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.13652"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(16)30045-X"},{"key":"e_1_2_12_18_1","unstructured":"Ostfold Hospital Trust.Prolonging the response by low\u2010dose rituximab maintenance therapy in immune thrombocytopenia: a randomized placebo\u2010controlled trial \u2010 the PROLONG Trial. 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