{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:59:04Z","timestamp":1760785144235,"version":"3.40.5"},"reference-count":6,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2023,6,14]],"date-time":"2023-06-14T00:00:00Z","timestamp":1686700800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Br J Haematol"],"published-print":{"date-parts":[[2023,8]]},"abstract":"<jats:p>The study by Kambhampati et al. offers the first European perspective on cost\u2010effectiveness of pola\u2010R\u2010CHP in the frontline line treatment of DLBCL patients. Nevertheless, the applicability of these results in other European settings remain questionable: Germany is indeed a wealthy country with wide access to cellular therapies in earlier lines, while this might not be the case for other European countries. The presented data must be re\u2010assessed when long term data on PFS and OS from the POLARIX trial are available, ideally considering also real\u2010life data. Similar CEAs in other European health care systems as well as in specific subgroups of patients are welcome to offer a broader perspective on the potential role of pola\u2010R\u2010CHP in Europe.<\/jats:p><jats:p>Commentary on: Kambhampati et al. Cost effectiveness of polatuzumab vedotin in combination with chemoimmunotherapy (pola\u2010R\u2010CHP) in previously untreated diffuse large B\u2010cell lymphoma in Germany. Br J Haematol 2023;202:771\u2013775.<\/jats:p>","DOI":"10.1111\/bjh.18934","type":"journal-article","created":{"date-parts":[[2023,6,14]],"date-time":"2023-06-14T10:09:00Z","timestamp":1686737340000},"page":"731-733","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["<scp>Pola\u2010R\u2010CHP<\/scp> for frontline therapy in <scp>DLBCL<\/scp>: Are we saving money by spending more?"],"prefix":"10.1111","volume":"202","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7772-2747","authenticated-orcid":false,"given":"U.","family":"Vitolo","sequence":"first","affiliation":[{"name":"Medical Oncology Candiolo Cancer Institute, FPO\u2010IRCCS  Candiolo Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. M. M.","family":"Frascione","sequence":"additional","affiliation":[{"name":"Medical Oncology Candiolo Cancer Institute, FPO\u2010IRCCS  Candiolo Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Bonello","sequence":"additional","affiliation":[{"name":"Medical Oncology Candiolo Cancer Institute, FPO\u2010IRCCS  Candiolo Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,6,14]]},"reference":[{"key":"e_1_2_2_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.18869"},{"key":"e_1_2_2_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2115304"},{"key":"e_1_2_2_4_1","doi-asserted-by":"publisher","DOI":"10.6004\/jadpro.2023.14.1.6"},{"key":"e_1_2_2_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.beha.2023.101441"},{"key":"e_1_2_2_6_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2022016624"},{"key":"e_1_2_2_7_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.22.00478"}],"container-title":["British Journal of Haematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bjh.18934","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,9]],"date-time":"2024-09-09T02:34:12Z","timestamp":1725849252000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/bjh.18934"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,14]]},"references-count":6,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["10.1111\/bjh.18934"],"URL":"https:\/\/doi.org\/10.1111\/bjh.18934","archive":["Portico"],"relation":{},"ISSN":["0007-1048","1365-2141"],"issn-type":[{"type":"print","value":"0007-1048"},{"type":"electronic","value":"1365-2141"}],"subject":[],"published":{"date-parts":[[2023,6,14]]},"assertion":[{"value":"2023-05-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-06-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-06-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}