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A total of 203 patients with AML diagnosed and managed at Jamhuriat Hospital from 1 March 2018 to 31 March 2020, were included in the current study. The median age at diagnosis was 27\u2009years. Housewives represented the largest subset of patients from an occupational point of view constituting 37.44% of the total sample population and 81.72% of the female population, followed by 20.69% patients who were students of which 14.77% were male and 5.91% were female, and 17.24% were farmers, which constituted 31.81% of the male population. Similarly, 69.95% of individuals presented with infection, 57.14% presented with bone tenderness, 46.3% presented with bleeding tendencies, 55.66% had hepatomegaly and\/or splenomegaly, and 27.58% of patients had lymphadenopathy. Considering the chemotherapeutic regime,\u00a064.53% of the individuals received standard 7\u2009+\u20093 (cytarabine\u2009+\u2009daunorubicin) induction regimen, 10.68% of those received 5\u2009+\u20092 re\u2010induction chemotherapy (cytarabine\u2009+\u2009daunorubicin). 10.84% who were diagnosed with acute promyelocytic leukaemia received all\u2010<jats:italic>trans<\/jats:italic>\u2010retinoic acid\u2009+\u2009arsenic trioxide, while 5.42% of patients defaulted chemotherapy. High prevalence was noted in young individuals. Similarly, a high proportion of patients were constituted by housewives.<\/jats:p>","DOI":"10.1111\/bjh.19029","type":"journal-article","created":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T08:24:23Z","timestamp":1692779063000},"page":"404-410","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Demographic and clinical characteristics of acute myeloid leukaemia diagnosed and treated at the tertiary level in Afghanistan"],"prefix":"10.1111","volume":"203","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5027-5585","authenticated-orcid":false,"given":"Sarah","family":"Noor","sequence":"first","affiliation":[{"name":"Department of Haemato\u2010Oncology Jamhuriat Hospital  Kabul Afghanistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4554-8024","authenticated-orcid":false,"given":"Ahmed Maseh","family":"Haidary","sequence":"additional","affiliation":[{"name":"Department of Pathology French Medical Institute for Mothers and Children (FMIC)  Kabul Afghanistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmad Walid","family":"Yosufzai","sequence":"additional","affiliation":[{"name":"Department of Haemato\u2010Oncology Jamhuriat Hospital  Kabul Afghanistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirajan","family":"Niazai","sequence":"additional","affiliation":[{"name":"Department of Haemato\u2010Oncology Jamhuriat Hospital  Kabul Afghanistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sahar","family":"Noor","sequence":"additional","affiliation":[{"name":"Department of Paediatric Medicine French Medical Institute for Mothers and Children (FMIC)  Kabul Afghanistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Najla","family":"Nasir","sequence":"additional","affiliation":[{"name":"Department of Medicine Rabia Balkhi Women's Hospital  Kabul Afghanistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayub","family":"Shinwari","sequence":"additional","affiliation":[{"name":"Department of Haemato\u2010Oncology Jamhuriat Hospital  Kabul Afghanistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8268-6111","authenticated-orcid":false,"given":"Ramin","family":"Saadaat","sequence":"additional","affiliation":[{"name":"Department of Pathology French Medical Institute for Mothers and Children (FMIC)  Kabul Afghanistan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,8,23]]},"reference":[{"key":"e_1_2_16_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells8080805"},{"key":"e_1_2_16_3_1","doi-asserted-by":"publisher","DOI":"10.2174\/1568009620666200424150321"},{"key":"e_1_2_16_4_1","doi-asserted-by":"publisher","DOI":"10.1596\/978-1-4648-0349-9_ch7"},{"key":"e_1_2_16_5_1","doi-asserted-by":"publisher","DOI":"10.5045\/br.2020.S001"},{"key":"e_1_2_16_6_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood\u20102011\u201001\u2010293050"},{"key":"e_1_2_16_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-017-0543-7"},{"key":"e_1_2_16_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.15032"},{"key":"e_1_2_16_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11912-020-00987-8"},{"key":"e_1_2_16_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature22993"},{"key":"e_1_2_16_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2015.00280"},{"key":"e_1_2_16_12_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2020.00480"},{"key":"e_1_2_16_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.14823"},{"key":"e_1_2_16_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-16-S1-S5"},{"key":"e_1_2_16_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-018-0156-2"},{"key":"e_1_2_16_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-020-00908-z"},{"key":"e_1_2_16_17_1","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2019.0028"},{"key":"e_1_2_16_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2019.04.005"},{"key":"e_1_2_16_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-017-3150-3"},{"key":"e_1_2_16_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdw025"},{"key":"e_1_2_16_21_1","doi-asserted-by":"publisher","DOI":"10.4103\/1658-5127.155171"},{"key":"e_1_2_16_22_1","unstructured":"AsifN HassanKS.Acute Myeloid Leukemia amongst Adults. 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