{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T11:35:29Z","timestamp":1773142529409,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,1,14]],"date-time":"2024-01-14T00:00:00Z","timestamp":1705190400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,1,14]],"date-time":"2024-01-14T00:00:00Z","timestamp":1705190400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Br J Haematol"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>Immune thrombocytopenia (ITP) resolves in most children within 3\u201312\u2009months of diagnosis. Chronic ITP affects 10%\u201320% of patients, some of whom require treatment. Several second\u2010line agents are efficacious in this group of patients. This paper describes our experience of using dapsone as a single second\u2010line agent in children with chronic ITP. One hundred and three children with chronic ITP were seen at our centre from January 2012 to December 2016. Forty\u2010five children met the inclusion criteria and received dapsone; 17 (37.8%) were boys; and 28 (62.2%) were girls. Early response to dapsone was seen in 37.8% of patients. The median duration of long\u2010term follow\u2010up was 50\u2009months, and at least a partial response was seen in 64.4% of the patients. Dapsone offers good initial response rates and sustained remission in paediatric chronic ITP, comparable to other therapeutic agents available.<\/jats:p>","DOI":"10.1111\/bjh.19277","type":"journal-article","created":{"date-parts":[[2024,1,14]],"date-time":"2024-01-14T20:34:06Z","timestamp":1705264446000},"page":"1024-1028","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Dapsone for paediatric chronic immune thrombocytopenia: Short\u00a0report from a tertiary centre in South India"],"prefix":"10.1111","volume":"204","author":[{"given":"Niteesh","family":"Bharadwaj","sequence":"first","affiliation":[{"name":"Pediatric Hematology Oncology St John's Medical College Hospital  Bengaluru Karnataka India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jyothi","family":"Munireddy","sequence":"additional","affiliation":[{"name":"Pediatric Hematology Oncology St John's Medical College Hospital  Bengaluru Karnataka India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sumithra","family":"Selvam","sequence":"additional","affiliation":[{"name":"St Johns Research Institute  Bengaluru Karnataka India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7821-7822","authenticated-orcid":false,"given":"Vandana","family":"Bharadwaj","sequence":"additional","affiliation":[{"name":"Pediatric Hematology Oncology St John's Medical College Hospital  Bengaluru Karnataka India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anand","family":"Prakash","sequence":"additional","affiliation":[{"name":"Pediatric Hematology Oncology St John's Medical College Hospital  Bengaluru Karnataka India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,1,14]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13312-012-0195-1"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2019000966"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.25086"},{"key":"e_1_2_15_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1700978"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2011.06.018"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1991.tb04467.x"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2015-03-632000"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.2005.00545.x"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.4274\/Tjh.2012.0049"},{"key":"e_1_2_15_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(15)61107\u20102"},{"key":"e_1_2_15_12_1","doi-asserted-by":"publisher","DOI":"10.1182\/asheducation.V2012.1.306.3798320"},{"key":"e_1_2_15_13_1","doi-asserted-by":"publisher","DOI":"10.3109\/09537104.2014.886677"},{"key":"e_1_2_15_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/09537100802315110"},{"key":"e_1_2_15_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.22266"}],"container-title":["British Journal of Haematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bjh.19277","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/bjh.19277","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bjh.19277","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T21:20:20Z","timestamp":1771276820000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/bjh.19277"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1,14]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,3]]}},"alternative-id":["10.1111\/bjh.19277"],"URL":"https:\/\/doi.org\/10.1111\/bjh.19277","archive":["Portico"],"relation":{},"ISSN":["0007-1048","1365-2141"],"issn-type":[{"value":"0007-1048","type":"print"},{"value":"1365-2141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1,14]]},"assertion":[{"value":"2023-06-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}