{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T18:03:45Z","timestamp":1772820225982,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,2,27]],"date-time":"2024-02-27T00:00:00Z","timestamp":1708992000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Br J Haematol"],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Chronic myelomonocytic leukaemia (CMML) is a rare haematological disorder characterized by monocytosis and dysplastic changes in myeloid cell lineages. Accurate risk stratification is essential for guiding treatment decisions and assessing prognosis. This study aimed to validate the Artificial Intelligence Prognostic Scoring System for Myelodysplastic Syndromes (AIPSS\u2010MDS) in CMML and to assess its performance compared with traditional scores using data from a Spanish registry (<jats:italic>n<\/jats:italic>\u2009=\u20091343) and a Taiwanese hospital (<jats:italic>n<\/jats:italic>\u2009=\u200975). In the Spanish cohort, the AIPSS\u2010MDS accurately predicted overall survival (OS) and leukaemia\u2010free survival (LFS), outperforming the Revised\u2010IPSS score. Similarly, in the Taiwanese cohort, the AIPSS\u2010MDS demonstrated accurate predictions for OS and LFS, showing superiority over the IPSS score and performing better than the CPSS and molecular CPSS scores in differentiating patient outcomes. The consistent performance of the AIPSS\u2010MDS across both cohorts highlights its generalizability. Its adoption as a valuable tool for personalized treatment decision\u2010making in CMML enables clinicians to identify high\u2010risk patients who may benefit from different therapeutic interventions. Future studies should explore the integration of genetic information into the AIPSS\u2010MDS to further refine risk stratification in CMML and improve patient outcomes.<\/jats:p>","DOI":"10.1111\/bjh.19341","type":"journal-article","created":{"date-parts":[[2024,2,27]],"date-time":"2024-02-27T11:14:41Z","timestamp":1709032481000},"page":"1529-1535","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Validation of the Artificial Intelligence Prognostic Scoring System for Myelodysplastic Syndromes in chronic myelomonocytic leukaemia: A novel approach for improved risk stratification"],"prefix":"10.1111","volume":"204","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4838-6750","authenticated-orcid":false,"given":"Adrian","family":"Mosquera\u00a0Orgueira","sequence":"first","affiliation":[{"name":"Hematology University Hospital of Santiago de Compostela, IDIS  Santiago de Compostela 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