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We studied a cohort of patients with stage I disease, diagnosed between 2006 and 2018, from six centres between Australia, Canada and Denmark. Our goal was to characterise outcomes, review treatment\u00a0and investigate the role of interim positron emission tomography (iPET). Thirty\u2010seven eligible patients were identified. The median duration of follow\u2010up was 42.2\u2009months. All received chemoimmunotherapy with 91.9% (<jats:italic>n<\/jats:italic>\u2009=\u200934) given rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone (R\u2010CHOP). 35.1% (<jats:italic>n<\/jats:italic>\u2009=\u200913) underwent consolidative radiotherapy. Eighteen patients were <jats:italic>H. pylori<\/jats:italic> positive and 11 had the documentation of <jats:italic>H. pylori<\/jats:italic> eradication therapy. The 4\u2010year progression\u2010free survival and overall survival of R\u2010CHOP was 88% (95% CI: 71\u201395) and 91% (95% CI: 75\u201397) respectively. All patients who achieved a partial metabolic response or complete metabolic response on iPET went on to achieve complete response at the end of treatment. R\u2010CHOP\u2010based therapy with iPET assessment appears to offer favourable outcomes, with radiotherapy and <jats:italic>H. pylori<\/jats:italic> eradication therapy implemented on a case\u2010by\u2010case basis.<\/jats:p>","DOI":"10.1111\/bjh.19470","type":"journal-article","created":{"date-parts":[[2024,4,18]],"date-time":"2024-04-18T05:29:55Z","timestamp":1713418195000},"page":"534-541","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Primary gastric diffuse large B\u2010cell lymphoma: A multicentre retrospective study"],"prefix":"10.1111","volume":"205","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4137-8096","authenticated-orcid":false,"given":"Cameron S.","family":"Lewis","sequence":"first","affiliation":[{"name":"Department of Haematology Sir Charles Gairdner Hospital  Nedlands Western Australia Australia"},{"name":"Department of Haematology Peter MacCallum Cancer Centre and Royal Melbourne Hospital 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