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Owing to significant advances, CAR\u2010T\u2010cell therapeutic modality has undergone substantial shifts in its clinical application. Coagulation abnormalities, which are prevalent complications in CAR\u2010T\u2010cell therapy, can range in severity from simple abnormalities in coagulation parameters to serious haemorrhage or disseminated intravascular coagulation associated with life\u2010threatening multiorgan dysfunction. Nonetheless, there is a lack of a comprehensive overview concerning the coagulation abnormalities associated with CAR\u2010T\u2010cell therapy. With an aim to attract heightened clinical focus and to enhance the safety of CAR\u2010T\u2010cell therapy, this review presents the characteristics of the coagulation abnormalities associated with CAR\u2010T\u2010cell therapy, including clinical manifestations, coagulation parameters, pathogenesis, risk factors and their influence on treatment efficacy in patients receiving CAR\u2010T\u2010cell infusion. 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