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In this retrospective single\u2010centre cohort study, we compared all ITP patients relapsed or non\u2010responsive to glucocorticoid therapy treated with either continuous TPO\u2010RAs (<jats:italic>n<\/jats:italic>\u2009=\u200935) or rituximab induction (<jats:italic>n<\/jats:italic>\u2009=\u200920) between 2015 and 2022. While both groups showed high initial complete response rates (CR, 68.6 vs. 80.0%, ns), the overall rate of progression to the next therapy was higher after time\u2010limited rituximab (75.0 vs. 42.9%), resulting in a lower relapse\u2010free survival (median 16.6 vs. 25.8\u2009months, log\u2010rank; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). We conclude that both treatments show similar initial efficacy and their ideal duration of therapy warrants further investigation.<\/jats:p>","DOI":"10.1111\/bjh.19629","type":"journal-article","created":{"date-parts":[[2024,7,8]],"date-time":"2024-07-08T05:04:30Z","timestamp":1720415070000},"page":"1121-1125","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Efficacy of thrombopoietin receptor agonists versus rituximab in non\u2010responsive immune thrombocytopenia\u2014A single centre retrospective analysis"],"prefix":"10.1111","volume":"205","author":[{"given":"Sebastian M.","family":"Stolz","sequence":"first","affiliation":[{"name":"Department of Medical Oncology and Hematology University Hospital of Zurich  Zurich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahel","family":"Schwotzer","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology and Hematology 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