{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T22:07:27Z","timestamp":1792534047758,"version":"4.5.0"},"reference-count":106,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T00:00:00Z","timestamp":1722988800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100021117","name":"Liverpool University Hospitals NHS Foundation Trust","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100021117","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Br J Haematol"],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>There has been an expansion in our understanding of the multifaceted roles of circulating blood cells in regulating haemostasis and contributing to thrombosis. Notably, there is greater recognition of the interplay between coagulation with inflammation and innate immune activation and the contribution of leucocytes. The full blood count (FBC) is a time\u2010honoured test in medicine; however, its components are often viewed in isolation and without consideration of their haemostatic and thrombotic potential. Here, we review how the individual components of the FBC, that is, haemoglobin, platelets and leucocytes, engage with the haemostatic system and focus on both their quantitative and qualitative attributes. We also explore how this information can be harnessed into better management of people with multiple long\u2010term conditions because of their higher risk of adverse clinical events.<\/jats:p>","DOI":"10.1111\/bjh.19690","type":"journal-article","created":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T17:53:11Z","timestamp":1723053191000},"page":"1269-1278","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Revisiting the full blood count: Circulating blood cells and their role in coagulation"],"prefix":"10.1111","volume":"205","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2761-913X","authenticated-orcid":false,"given":"Jeremy","family":"Schofield","sequence":"first","affiliation":[{"name":"Department of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences University of Liverpool  Liverpool UK"},{"name":"Roald Dahl Haemostasis &amp; Thrombosis Centre Liverpool University Hospitals NHS Foundation Trust  Liverpool UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Yong","sequence":"additional","affiliation":[{"name":"Department of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences University of Liverpool  Liverpool UK"},{"name":"Roald Dahl Haemostasis &amp; Thrombosis Centre Liverpool University Hospitals NHS Foundation Trust  Liverpool UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9708-8883","authenticated-orcid":false,"given":"Cheng\u2010Hock","family":"Toh","sequence":"additional","affiliation":[{"name":"Department of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences University of Liverpool  Liverpool UK"},{"name":"Roald Dahl Haemostasis &amp; Thrombosis Centre Liverpool University Hospitals NHS Foundation Trust  Liverpool 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