{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T23:02:55Z","timestamp":1771110175670,"version":"3.50.1"},"reference-count":10,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T00:00:00Z","timestamp":1728950400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T00:00:00Z","timestamp":1728950400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Br J Haematol"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:p>Jayne et\u00a0al. provide a molecular characterization of the t(1;6)(p35.3;p25.2) chromosomal translocation in patients with chronic lymphocytic leukaemia. They indicate that this translocation involves the gene encoding interferon regulatory factor 4 (IRF4) on chromosome 6p25.2 with the regulator of chromosome condensation 1 (RCC1) gene on chromosome 1p35.3. This translocations may have important prognostic value.<\/jats:p>\n                  <jats:p>\n                    Commentary on: Jayne et\u00a0al. The chromosomal translocation t(1;6)(p35.3;p25.2), recurrent in chronic lymphocytic leukaemia leads to\n                    <jats:italic>RCC1<\/jats:italic>\n                    ::\n                    <jats:italic>IRF4<\/jats:italic>\n                    fusion. Br J Haematol 2024; 205:\n                    <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"https:\/\/doi.org\/10.1111\/bjh.19790\">2321\u20102326<\/jats:ext-link>\n                    .\n                  <\/jats:p>","DOI":"10.1111\/bjh.19821","type":"journal-article","created":{"date-parts":[[2024,10,16]],"date-time":"2024-10-16T01:25:26Z","timestamp":1729041926000},"page":"2125-2127","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The discovery of the\n                    <scp>RCC1<\/scp>\n                    ::\n                    <scp>IRF4<\/scp>\n                    Fusion in\n                    <scp>CLL<\/scp>\n                    patients with t(1;6)(p35.3;p25.2) chromosomal translocation"],"prefix":"10.1111","volume":"205","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2270-2997","authenticated-orcid":false,"given":"Anna E.","family":"Pula","sequence":"first","affiliation":[{"name":"Department of Hematology Medical University of Lodz  Lodz Poland"},{"name":"Section of Hematology\/Oncology University of Chicago  Chicago Illinois USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3411-6357","authenticated-orcid":false,"given":"Tadeusz","family":"Robak","sequence":"additional","affiliation":[{"name":"Department of Hematology Medical University of Lodz  Lodz Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,10,15]]},"reference":[{"key":"e_1_2_2_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.19790"},{"key":"e_1_2_2_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature14666"},{"key":"e_1_2_2_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/gcc.22994"},{"key":"e_1_2_2_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14174314"},{"key":"e_1_2_2_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10238-022-00968-0"},{"key":"e_1_2_2_7_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2020.00225"},{"key":"e_1_2_2_8_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-09-873083"},{"key":"e_1_2_2_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-019-0239-8"},{"key":"e_1_2_2_10_1","doi-asserted-by":"publisher","DOI":"10.1182\/asheducation-2017.1.329"},{"key":"e_1_2_2_11_1","unstructured":"MitevL GrahlyovaL.Del(6q) in Chronic lymphocytic leukaemia (CLL). Available from:https:\/\/atlasgeneticsoncology.org\/haematological\/2011\/del(6q)\u2010in\u2010chronic\u2010lymphocytic\u2010leukaemia\u2010(cll). Accessed 20 September 2024"}],"container-title":["British Journal of Haematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bjh.19821","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/bjh.19821","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bjh.19821","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T22:11:39Z","timestamp":1771107099000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/bjh.19821"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,15]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["10.1111\/bjh.19821"],"URL":"https:\/\/doi.org\/10.1111\/bjh.19821","archive":["Portico"],"relation":{},"ISSN":["0007-1048","1365-2141"],"issn-type":[{"value":"0007-1048","type":"print"},{"value":"1365-2141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,15]]},"assertion":[{"value":"2024-09-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}