{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T09:46:19Z","timestamp":1765791979118,"version":"3.48.0"},"reference-count":10,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,3,9]],"date-time":"2025-03-09T00:00:00Z","timestamp":1741478400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Br J Haematol"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1111\/bjh.20034","type":"journal-article","created":{"date-parts":[[2025,3,10]],"date-time":"2025-03-10T05:35:32Z","timestamp":1741584932000},"page":"1513-1517","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A pilot study tracking immune cell subsets and activation profiles in adults with haemophagocytic lymphohistiocytosis treated with anakinra"],"prefix":"10.1111","volume":"206","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6058-1036","authenticated-orcid":false,"given":"Mark J.","family":"Bishton","sequence":"first","affiliation":[{"name":"School of Medicine University of Nottingham  Nottingham UK"},{"name":"Nottingham University Hospitals, National Health Service Trust  Nottingham UK"},{"name":"National Disease Registration Service, National Health Service England  Leeds UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emma","family":"Hadfield","sequence":"additional","affiliation":[{"name":"Nottingham University Hospitals, National Health Service Trust  Nottingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Onion","sequence":"additional","affiliation":[{"name":"School of Life Sciences University of Nottingham  Nottingham UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,3,9]]},"reference":[{"key":"e_1_2_2_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2014.03.002"},{"key":"e_1_2_2_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.21039"},{"key":"e_1_2_2_4_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2018894618"},{"key":"e_1_2_2_5_1","unstructured":"England N.Anakinra for haemophagocytic lymphohistiocytosis for adults and children in all ages.2021. Available from:https:\/\/www.england.nhs.uk\/publication\/anakinra\u2010for\u2010haemophagocytic\u2010lymphohistiocytosis\u2010for\u2010adults\u2010and\u2010children\u2010in\u2010all\u2010ages\/"},{"key":"e_1_2_2_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/21505594.2024.2342276"},{"key":"e_1_2_2_7_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2020009499"},{"key":"e_1_2_2_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.38690"},{"key":"e_1_2_2_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15061914"},{"key":"e_1_2_2_10_1","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2023012217"},{"key":"e_1_2_2_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(19)30156-5"}],"container-title":["British Journal of Haematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bjh.20034","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T09:43:02Z","timestamp":1765791782000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/bjh.20034"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,9]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["10.1111\/bjh.20034"],"URL":"https:\/\/doi.org\/10.1111\/bjh.20034","archive":["Portico"],"relation":{},"ISSN":["0007-1048","1365-2141"],"issn-type":[{"type":"print","value":"0007-1048"},{"type":"electronic","value":"1365-2141"}],"subject":[],"published":{"date-parts":[[2025,3,9]]},"assertion":[{"value":"2024-12-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}