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Targeting antiapoptotic <jats:italic>BCL\u20102<\/jats:italic> family proteins has demonstrated therapeutic efficacy in ETP\u2010ALL with agents such as venetoclax. We present a case series of five adult patients with relapsed or refractory (R\/R) ETP\u2010ALL who were treated with a hypomethylating agent (HMA) in combination with venetoclax (HMA\u2010VEN) and demonstrate that this therapy is efficacious and can bridge responders to allogeneic stem cell transplantation with curative intent.<\/jats:p>","DOI":"10.1111\/bjh.20065","type":"journal-article","created":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T00:02:18Z","timestamp":1744243338000},"page":"1678-1682","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Hypomethylating agent and venetoclax are effective salvage therapies in relapsed\/refractory early T\u2010cell precursor acute lymphoblastic leukaemia"],"prefix":"10.1111","volume":"206","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6383-3777","authenticated-orcid":false,"given":"Vaibhav","family":"Agrawal","sequence":"first","affiliation":[{"name":"Department 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