{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T05:49:49Z","timestamp":1782107389086,"version":"3.54.5"},"reference-count":25,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T00:00:00Z","timestamp":1768176000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T00:00:00Z","timestamp":1768176000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Br J Haematol"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>Hepatitis\u2010associated aplastic anaemia is a rare entity that can sometimes be life\u2010threatening due to its rapid progression to liver failure, necessitating an urgent liver transplantation (LT). Treating severe aplastic anaemia following an LT can be very challenging. While immunosuppressive therapy (IST) has been reported to have some success, the vulnerable state of these patients in addition to the time taken for IST to work makes this a less suitable option for the majority of patients. Haematopoietic stem cell transplantation (HSCT) with matched related donors has been reported as a curative option; there has been less success using alternate donors. Here, we present our experience of predominantly alternate donor HSCT following liver transplantation in an extremely high\u2010risk group of 10 children. Overall survival was 90% at a median of 38\u2009months post\u2010LT. Surviving children have normal blood counts, normal liver function and performance status. No liver\u2010related complications or significant graft versus host disease were encountered. Multiple infective and non\u2010infective post\u2010HSCT complications were successfully treated with excellent multidisciplinary input. Upfront HSCT, even with alternate donors, can be lifesaving if performed in a timely manner, following close liaison between liver transplantation and HSCT teams and with the appropriate multidisciplinary support.<\/jats:p>","DOI":"10.1111\/bjh.70328","type":"journal-article","created":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T08:07:05Z","timestamp":1768291625000},"page":"1009-1016","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Excellent outcomes in children after haematopoietic stem cell transplantation for hepatitis\u2010associated aplastic anaemia following liver transplantation"],"prefix":"10.1111","volume":"208","author":[{"given":"Satish Kumar","family":"Meena","sequence":"first","affiliation":[{"name":"Great Ormond Street Hospital for Children NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adarsh","family":"Kancharla","sequence":"additional","affiliation":[{"name":"King's College Hospital NHS Foundation Trust  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amany I.","family":"Mohamed","sequence":"additional","affiliation":[{"name":"Leeds Children's Hospital Leeds Teaching Hospital NHS Trust  Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beki","family":"James","sequence":"additional","affiliation":[{"name":"Leeds Children's Hospital Leeds Teaching Hospital NHS Trust  Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna\u2010Maria","family":"Ewins","sequence":"additional","affiliation":[{"name":"Royal Hospital for Children  Glasgow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahzya","family":"Chaudhury","sequence":"additional","affiliation":[{"name":"Royal Hospital for Children  Glasgow 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