{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T09:00:35Z","timestamp":1780909235779,"version":"3.54.1"},"reference-count":32,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T00:00:00Z","timestamp":1771372800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T00:00:00Z","timestamp":1771372800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100008897","name":"Janssen Pharmaceutica","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008897","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016469","name":"Takeda Pharmaceuticals International","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016469","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Br J Haematol"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>Selecting eligible allogeneic haematopoietic stem cell transplantation (allo\u2010HSCT) candidates with low\u2010risk and intermediate\u2010risk myelodysplastic syndrome (MDS) remains controversial. The International Working Group (IWG) for MDS prognosis identified a Revised International Prognostic Scoring System (IPSS\u2010R) score &gt;3.5 for benefits from early transplantation; the MDS\u2010RIGHT group uses a broader set of poor risk features. We analysed 1145 lower risk MDS (lower risk and intermediate\u2010risk IPSS\u2010R) patients aged &lt;75\u2009years, using real\u2010world European Myelodysplastic Syndromes registry data and identifying those meeting IWG or MDS\u2010RIGHT criteria for allo\u2010HSCT at baseline and 6\u2010month follow\u2010up. Fit patients were characterised by Karnofsky score \u226570 and Haematopoietic Cell Transplantation\u2010specific Comorbidity Index &lt;3. We evaluated clinical outcomes of transplant candidates, including survival, disease progression risk, new comorbidity risk and performance status decline. The IWG criterion, and not MDS\u2010RIGHT criteria, identified patients with lower risk and intermediate\u2010risk MDS with poorer baseline survival. Fit lower risk patients showed 2\u2010year cumulative risks of incident comorbidity and performance status deterioration of 20% and 5% respectively. In summary, IWG and MDS\u2010RIGHT features identify patients with lower or intermediate\u2010risk MDS as candidates for early transplantation. Lower risk patients fit for transplantation have a cumulative incidence of adverse outcomes possibly jeopardising transplantation eligibility and should be carefully selected when planning delayed transplantation strategies.<\/jats:p>","DOI":"10.1111\/bjh.70384","type":"journal-article","created":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T08:16:02Z","timestamp":1771402562000},"page":"1734-1744","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinical outcomes of patients with lower risk myelodysplastic syndrome from\n                    <scp>EUMDS<\/scp>\n                    registry eligible for transplantation: Implications for transplantation strategies"],"prefix":"10.1111","volume":"208","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5619-3724","authenticated-orcid":false,"given":"Aleksandar","family":"Savic","sequence":"first","affiliation":[{"name":"Clinic of Hematology, University Clinical Center of Vojvodina, Faculty of Medicine University of Novi Sad  Novi Sad Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7793-8222","authenticated-orcid":false,"given":"Adele","family":"Taylor","sequence":"additional","affiliation":[{"name":"Epidemiology and Cancer Statistics Group, Department of Health Sciences University of York  York UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0468-3553","authenticated-orcid":false,"given":"Pierre","family":"Fenaux","sequence":"additional","affiliation":[{"name":"Service d'H\u00e9matologie, H\u00f4pital Saint\u2010Louis, Assistance Publique des H\u00f4pitaux de Paris (AP\u2010HP) and Universit\u00e9 Paris 7  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3685-3473","authenticated-orcid":false,"given":"Argiris","family":"Symeonidis","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of Hematology, University of Patras Medical School, Olympion Hospital &amp; Rehabilitation Center  Patras Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5185-0190","authenticated-orcid":false,"given":"Catherine","family":"Cargo","sequence":"additional","affiliation":[{"name":"Haematological Malignancy Diagnostic Service, Leeds Cancer Centre St James's University Hospital &amp; Leeds Teaching Hospitals NHS Trust  Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7677-9119","authenticated-orcid":false,"given":"Moshe","family":"Mittelman","sequence":"additional","affiliation":[{"name":"Department of Medicine A, Tel Aviv Sourasky (Ichilov) Medical Center and Sackler Medical Faculty Tel Aviv University  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9205-1440","authenticated-orcid":false,"given":"Verena","family":"Petzer","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine V (Haematology and Oncology) Innsbruck Medical University  Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2767-8191","authenticated-orcid":false,"given":"Guillermo","family":"Sanz","sequence":"additional","affiliation":[{"name":"Department of Haematology Hospital Universitario y Polit\u00e9cnico La Fe  Valencia Spain"},{"name":"Health Research Institute La Fe  Valencia Spain"},{"name":"CIBERONC, ISCIII  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaroslav","family":"\u010cerm\u00e1k","sequence":"additional","affiliation":[{"name":"Department of Clinical Hematology Institute of Hematology &amp; Blood Transfusion  Praha Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0366-0800","authenticated-orcid":false,"given":"Saskia","family":"Langemeijer","sequence":"additional","affiliation":[{"name":"Department of Hematology Radboud University Medical Center  Nijmegen The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7839-3743","authenticated-orcid":false,"given":"Eva","family":"Hellstr\u00f6m\u2010Lindberg","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division Hematology, Center for Hematology and Regenerative Medicine Karolinska Institutet  Stockholm 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