{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T06:13:42Z","timestamp":1789193622772,"version":"build-2803163510"},"reference-count":19,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T00:00:00Z","timestamp":1784246400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T00:00:00Z","timestamp":1784246400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Br J Haematol"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    While end\u2010of\u2010treatment (EOT) imaging after front\u2010line therapy is prognostic in nodal peripheral T\u2010cell lymphoma (PTCL), its subtype\u2010specific significance remains unclear. Retrospective review of patients with nodal PTCL included in the Australasian Lymphoma and Related Diseases Registry and the Princess Margaret Cancer Centre lymphoma database between 2011 and 2024. Progression\u2010free survival (PFS), overall survival (OS), and positive and negative predictive values (PPV\/NPV) of an EOT positron emission tomography\/computed tomography response were evaluated. We identified 451 patients. Median follow\u2010up was 43.1\u2010months (95% confidence interval [CI] 38.8%\u201348.3%). Patients achieving an EOT imaging complete remission (CR) had a 36\u2010month PFS of 43.1% (95% CI 34.3%\u201351.5%). The 36\u2010month OS was significantly higher in patients achieving CR compared with those who did not achieve a CR (73.5% [95% CI 65.3%\u201380%] vs. 20.9% [95% CI 12.9%\u201330.2%];\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). EOT imaging CR remained prognostic for OS in all nodal PTCL subtypes (\n                    <jats:italic>p<\/jats:italic>\n                    \u2009&lt;\u20090.001). At 36\u2010months, EOT PET demonstrated a PPV of 90% (95% CI 80.5%\u201396.2%) and a NPV of 43.1% (95% CI 34.3%\u201351.5%). EOT PET\/CT CR is strongly prognostic of OS across nodal PTCL subtypes with a high PPV for predicting death but poor NPV for predicting survival. Outcomes remain poor for patients not achieving a CR, with suboptimal outcomes even in those achieving CR.\n                  <\/jats:p>","DOI":"10.1111\/bjh.70689","type":"journal-article","created":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T01:52:02Z","timestamp":1784339522000},"page":"1057-1067","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["End\u2010of\u2010treatment positron emission tomography\/computed tomography complete remission is highly prognostic in nodal peripheral T\u2010cell lymphoma: An Australasian\u2010Canadian collaborative study"],"prefix":"10.1111","volume":"209","author":[{"given":"Chathuri","family":"Abeyakoon","sequence":"first","affiliation":[{"name":"Division of Medical Oncology and Haematology Princess Margaret Cancer Centre  Toronto Ontario Canada"},{"name":"Monash Haematology Monash Health  Melbourne Victoria Australia"},{"name":"Department of Medicine, School of Clinical Sciences at Monash Health Monash University  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cameron","family":"Wellard","sequence":"additional","affiliation":[{"name":"School of Public Health and Preventive Medicine Monash University  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa","family":"Murad","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging University Health Network  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliza","family":"Chung","sequence":"additional","affiliation":[{"name":"School of Public Health and Preventive Medicine Monash University  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Hodgson","sequence":"additional","affiliation":[{"name":"Division of Radiation Oncology Princess Margaret Cancer Centre  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle","family":"Rodin","sequence":"additional","affiliation":[{"name":"Division of Radiation Oncology Princess Margaret Cancer Centre  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anca","family":"Prica","sequence":"additional","affiliation":[{"name":"Division of Medical Oncology and Haematology Princess Margaret Cancer Centre  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6782-8361","authenticated-orcid":false,"given":"Tomohiro","family":"Aoki","sequence":"additional","affiliation":[{"name":"Division of Medical Oncology and Haematology Princess Margaret Cancer Centre  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5369-1501","authenticated-orcid":false,"given":"Abi","family":"Vijenthira","sequence":"additional","affiliation":[{"name":"Division of Medical Oncology and Haematology Princess Margaret Cancer Centre  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Umberto","family":"Falcone","sequence":"additional","affiliation":[{"name":"Division of Medical Oncology and Haematology Princess Margaret Cancer Centre  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0308-6458","authenticated-orcid":false,"given":"Stephen","family":"Opat","sequence":"additional","affiliation":[{"name":"Monash Haematology Monash Health  Melbourne Victoria Australia"},{"name":"Department of Medicine, School of Clinical Sciences at Monash Health Monash University  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7527-2340","authenticated-orcid":false,"given":"Erica M.","family":"Wood","sequence":"additional","affiliation":[{"name":"Monash Haematology Monash Health  Melbourne Victoria Australia"},{"name":"School of Public Health and Preventive Medicine Monash University  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9698-7185","authenticated-orcid":false,"given":"Zoe K.","family":"McQuilten","sequence":"additional","affiliation":[{"name":"Monash Haematology Monash Health  Melbourne Victoria Australia"},{"name":"School of Public Health and Preventive Medicine Monash University  Melbourne Victoria Australia"},{"name":"Alfred Health  Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0376-2559","authenticated-orcid":false,"given":"Eliza 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