{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T19:59:54Z","timestamp":1765742394377,"version":"build-2065373602"},"reference-count":36,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,8,6]],"date-time":"2015-08-06T00:00:00Z","timestamp":1438819200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Youthdale Foundation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["British J Health Psychol"],"published-print":{"date-parts":[[2016,2]]},"abstract":"\n Objectives<\/jats:title>\n \n Fatigue is a leading concern of patients with chronic hepatitis\n C<\/jats:styled-content>\n virus (\n HCV<\/jats:styled-content>\n ) infection. Despite its clinical significance, fatigue in\n HCV<\/jats:styled-content>\n is poorly understood and therefore invariably under\u2010treated. A cognitive\u2010behavioural approach offers a framework to understand and treat fatigue, but the characteristics of fatigue in chronic\n HCV<\/jats:styled-content>\n infection have not been documented from a cognitive\u2010behavioural perspective. This study captured the common and unique aspects of fatigue from a cognitive\u2010behavioural perspective in individuals with\n HCV<\/jats:styled-content>\n infection and clinically significant fatigue.\n <\/jats:p>\n <\/jats:sec>\n \n Design<\/jats:title>\n Cross\u2010sectional, qualitative using a critical realism approach.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Fourteen individuals (64% women; age >18\u00a0years) participated in semi\u2010structured interviews. The interviews documented the features, course, and perceived antecedents of fatigue; fatigue\u2010specific cognitions; fatigue management behaviours; and the functional impact of fatigue.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Participants' descriptions included the aspects of fatigue that have been targets of cognitive\u2010behavioural therapy in other medical conditions, including attributing fatigue to the illness; expectation of chronicity; low control; and fatigue\u2010driven coping. There were also components of fatigue experience that appear to be unique characteristics of fatigue related to\n HCV<\/jats:styled-content>\n , including predominantly physical fatigue; high acceptance of fatigue; and liver\u2010protective diet as a fatigue management behaviour.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n This was the first study to document the experience of fatigue in chronic\n HCV<\/jats:styled-content>\n infection in a cognitive\u2010behavioural framework. The findings suggest that the cognitive\u2010behavioural approach can be applied to fatigue in chronic\n HCV<\/jats:styled-content>\n infection. This would open an avenue to alleviate fatigue and thus improve the primary patient\u2010reported outcome of the disease.\n <\/jats:p>\n <\/jats:sec>\n \n \n \n \n \n Statement of contribution<\/jats:title>\n <\/jats:caption>\n \n \n What is already known on this subject?<\/jats:bold>\n <\/jats:italic>\n <\/jats:p>\n \n \n \n \n Fatigue is a key patient\u2010reported outcome measure of chronic hepatitis\n C<\/jats:styled-content>\n virus (\n HCV<\/jats:styled-content>\n ) infection.\n <\/jats:p>\n <\/jats:list-item>\n \n Fatigue management is not part of the standard care, because fatigue is poorly characterized in this population.<\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n \n \n What does this study add?<\/jats:bold>\n <\/jats:italic>\n <\/jats:p>\n \n \n \n \n A cognitive\u2010behavioural approach can be applied to understand fatigue in\n HCV<\/jats:styled-content>\n infection.\n <\/jats:p>\n <\/jats:list-item>\n \n Identified aspects of fatigue (antecedents, consequences, cognitions, behaviours) that can be treatment targets.<\/jats:p>\n <\/jats:list-item>\n \n \n Cognitive\u2010behavioural therapy would open a new treatment avenue to alleviate fatigue in\n HCV<\/jats:styled-content>\n infection.\n <\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:boxed-text>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/bjhp.12155","type":"journal-article","created":{"date-parts":[[2015,8,7]],"date-time":"2015-08-07T01:13:59Z","timestamp":1438910039000},"page":"157-172","source":"Crossref","is-referenced-by-count":12,"title":["Fatigue in chronic hepatitis\n C<\/scp>\n infection: Understanding patients' experience from a cognitive\u2010behavioural perspective"],"prefix":"10.1111","volume":"21","author":[{"given":"Dora","family":"Zalai","sequence":"first","affiliation":[{"name":"Department of Psychology Ryerson University Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colleen E.","family":"Carney","sequence":"additional","affiliation":[{"name":"Department of Psychology Ryerson University Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morris","family":"Sherman","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology University Health Network University of Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colin M.","family":"Shapiro","sequence":"additional","affiliation":[{"name":"Department of Psychiatry University Health Network University of Toronto Canada"},{"name":"Department of Ophthalmology University Health Network University of Toronto Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelly","family":"McShane","sequence":"additional","affiliation":[{"name":"Department of Psychology Ryerson University Toronto Ontario Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,8,6]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nlm.2011.12.004"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2008.05.003"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10865\u2010010\u20109266\u20108"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2011.08.001"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.5665\/SLEEP.1114"},{"volume-title":"Doing qualitative research","year":"1999","author":"Crabtree B. 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