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Direct\u2010acting antiviral treatment can cure almost all people infected with hepatitis C. However, the longer\u2010term impacts on within people's life trajectories are unknown, although some suggest it may lead to fundamental behavioural changes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>A cross\u2010sectional exploratory retrospective qualitative design.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We interviewed 30 people who inject(ed) drugs and who had previously been treated with direct\u2010acting antivirals on average 18\u2009months before the interview (range: 12\u201324\u2009months). Most were male, aged 36\u201355\u2009years, and had been treated in urban community\u2010based needle and syringe programmes in Scotland. All interviews were semi\u2010structured, conducted over the phone by either peer or academic researchers, and analysed thematically.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We present three discernible post\u2010treatment life\u2010trajectories. Firstly, \u2018\n                      <jats:italic>A cure that was like totally new life\u2019<\/jats:italic>\n                      involved identity transformation, often associated with controlled or zero drug use, and improved physical and mental health. Secondly, \u2018\n                      <jats:italic>There isn't much afterwards<\/jats:italic>\n                      \u2019 comprised poor quality of life and social isolation, often due to participants' disengagement from former drug use and support networks. Thirdly, \u2018\n                      <jats:italic>I'm getting tested every year now\u2019<\/jats:italic>\n                      detailed a few life changes but normalized hepatitis C testing and treatment.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our thematic analysis reinforces the positive impacts on mental well\u2010being, physical health and self\u2010transformation of direct\u2010acting antiviral treatment in the short\u2010 and long\u2010term. However, there is an urgent need for psychosocial interventions to maintain health behaviour changes and self\u2010management, and social support for individuals post hepatitis C treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bjhp.70005","type":"journal-article","created":{"date-parts":[[2025,7,12]],"date-time":"2025-07-12T05:13:47Z","timestamp":1752297227000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Post\u2010treatment life\u2010trajectories among people who inject drugs who completed hepatitis C treatment with direct acting antivirals: A thematic analysis"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9135-0684","authenticated-orcid":false,"given":"Gabriele","family":"Vojt","sequence":"first","affiliation":[{"name":"NIHR Health Protection Research Unit in Behavioural Science and Evaluation University of Bristol  Bristol UK"},{"name":"National Institute for Health and Care Research, Applied Research Collaboration West (NIHR ARC West) University Hospitals Bristol and Weston NHS Foundation Trust  Bristol UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7727-231X","authenticated-orcid":false,"given":"Lawrie","family":"Elliott","sequence":"additional","affiliation":[{"name":"School of Health &amp; Life Sciences Glasgow Caledonian University  Glasgow UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1243-778X","authenticated-orcid":false,"given":"Hannah","family":"Family","sequence":"additional","affiliation":[{"name":"NIHR Health Protection Research Unit in Behavioural Science and Evaluation University of Bristol  Bristol UK"},{"name":"National Institute for Health and Care Research, Applied Research Collaboration West (NIHR ARC West) University Hospitals Bristol and Weston NHS Foundation Trust  Bristol UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Sharkey","sequence":"additional","affiliation":[{"name":"Ninewells Hospital and Medical School NHS Tayside  Dundee UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Stephens","sequence":"additional","affiliation":[{"name":"Ninewells Hospital and Medical School NHS Tayside  Dundee UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6891-6758","authenticated-orcid":false,"given":"Sharon","family":"Hutchinson","sequence":"additional","affiliation":[{"name":"School of Health &amp; 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