{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T23:40:13Z","timestamp":1768693213401,"version":"3.49.0"},"reference-count":19,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,6,7]],"date-time":"2013-06-07T00:00:00Z","timestamp":1370563200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2013,8]]},"abstract":"\n Objectives<\/jats:title>\n \n \n \n To explore the prognostic role of hydronephrosis grade in patients with pure ureteric cancer.<\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>\n \n Patients and Methods<\/jats:title>\n \n \n \n \n The study included 162 patients with pure ureteric cancer who were treated between\n J<\/jats:styled-content>\n anuary 2005 and\n D<\/jats:styled-content>\n ecember 2010 at a single tertiary referral centre.\n <\/jats:p>\n <\/jats:list-item>\n \n \n The association between hydronephrosis grade with pathological findings and oncological outcomes was assessed using multivariate\n C<\/jats:styled-content>\n ox regression analysis.\n <\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n \n \n \n Hydronephrosis grade >2 was independently associated with non\u2010organ\u2010confined ureteric cancer (\n P<\/jats:italic>\n = 0.003).\n <\/jats:p>\n <\/jats:list-item>\n \n Hydronephrosis grade <2 was highly prevalent in organ\u2010confined disease.<\/jats:p>\n <\/jats:list-item>\n \n \n Hydronephrosis grade >2 and bladder cancer history independently predict bladder cancer recurrence (\n P<\/jats:italic>\n = 0.021 and\n P<\/jats:italic>\n = 0.002, respectively)\n <\/jats:p>\n <\/jats:list-item>\n \n \n Hydronephrosis of grade >2 was found to be associated with local and distant recurrence only in univariate analysis; non\u2010organ\u2010confined pathology independently predicted local and distant oncological failure (\n P<\/jats:italic>\n \u2264 0.001 and\n P<\/jats:italic>\n = 0.002, respectively).\n <\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n \n \n Hydronephrosis grade >2 is associated with non\u2010organ\u2010confined ureteric cancer and with bladder cancer recurrence.<\/jats:p>\n <\/jats:list-item>\n \n Non\u2010organ\u2010confined pathology is still the most important predictor for local and distant oncological failure.<\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/bju.12157","type":"journal-article","created":{"date-parts":[[2013,6,7]],"date-time":"2013-06-07T09:57:28Z","timestamp":1370599048000},"page":"489-494","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Severity of hydronephrosis correlates with tumour invasiveness and urinary bladder recurrence of ureteric cancer"],"prefix":"10.1111","volume":"112","author":[{"given":"Hao Lun","family":"Luo","sequence":"first","affiliation":[{"name":"Graduate Institute of Medicine College of Medicine Kaohsiung Medical University Taiwan"},{"name":"Department of Urology Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chih Hsiung","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Urology Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yen Ta","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Urology Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yao Chi","family":"Chuang","sequence":"additional","affiliation":[{"name":"Department of Urology Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei Ching","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Urology Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine Kaohsiung Taiwan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan Tso","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Urology Kaohsiung Chang Gung 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