{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T14:01:51Z","timestamp":1779112911272,"version":"3.51.4"},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2013,6,14]],"date-time":"2013-06-14T00:00:00Z","timestamp":1371168000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2013,9]]},"abstract":"\n Objectives<\/jats:title>\n \n \n \n \n To investigate if absorption of irrigation fluid occurs during bipolar plasma vaporisation (\n BPV<\/jats:styled-content>\n ) of the prostate.\n <\/jats:p>\n <\/jats:list-item>\n \n \n To examine the clinical predictors of increased risk of fluid absorption and to assess if changes in serum electrolytes, venous\n pH<\/jats:styled-content>\n , haemoglobin or haematocrit are able to detect intra\u2010operative fluid absorption.\n <\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>\n \n Patients and Methods<\/jats:title>\n \n \n \n \n Over a 15\u2010month period, 55 consecutive patients undergoing\n BPV<\/jats:styled-content>\n of the prostate were investigated.\n <\/jats:p>\n <\/jats:list-item>\n \n The volume of intra\u2010operative fluid absorption was measured using expired\u2010breath ethanol measurements.<\/jats:p>\n <\/jats:list-item>\n \n Intra\u2010operative irrigation was performed with isotonic saline containing 1% ethanol. The breath ethanol concentration was measured every 10\u2009min during the operation and the volume of irrigation fluid absorption was calculated from these concentrations.<\/jats:p>\n <\/jats:list-item>\n \n \n Data on clinical (age, prostate volume, smoking status) and surgical variables (operation time, irrigation volume, appearance of capsular perforation) as well as intra\u2010operative changes in serum electrolytes, venous\n pH<\/jats:styled-content>\n , haemoglobin and haematocrit were recorded.\n <\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n \n \n The median (range) age of the patients was 67 (48\u201387) years and the median (range) prostate volume was 41 (17\u2013111) mL.<\/jats:p>\n <\/jats:list-item>\n \n Nine patients (16%) showed a positive ethanol breath test during the procedure. The median (range) calculated fluid absorption in these patients was 346 (138\u20132166) mL.<\/jats:p>\n <\/jats:list-item>\n \n Three patients had a fluid absorption >500\u2009mL. One patient with absorption of >2\u2009L showed clinical symptoms (dyspnoea and agitation) during the operation under spinal anaesthesia.<\/jats:p>\n <\/jats:list-item>\n \n \n I<\/jats:styled-content>\n n the group of patients with fluid absorption, capsular perforation or injury to larger vessels was more often detectable.\n <\/jats:p>\n <\/jats:list-item>\n \n \n In the group of patients with fluid absorption, only venous\n pH<\/jats:styled-content>\n showed a significant change during the operation (from median 7.41 to median 7.34,\n P<\/jats:italic>\n = 0.02). The\n pH<\/jats:styled-content>\n decrease was significantly greater in the fluid absorption group than in the group of patients without fluid absorption (0.09 vs. 0.02,\n P<\/jats:italic>\n = 0.005).\n <\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n \n \n \n We have demonstrated that significant intra\u2010operative fluid absorption can occur during\n BPV<\/jats:styled-content>\n of the prostate. Care must be taken if using this procedure in patients with significant cardiovascular comorbidities.\n <\/jats:p>\n <\/jats:list-item>\n \n Respecting the anatomical borders of the prostate seems to play a relevant role in preventing fluid absorption during the procedure.<\/jats:p>\n <\/jats:list-item>\n \n \n Venous\n pH<\/jats:styled-content>\n could be used to detect potentially dangerous fluid absorption if intra\u2010operative monitoring with breath ethanol measurements is not available.\n <\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/bju.12170","type":"journal-article","created":{"date-parts":[[2013,6,14]],"date-time":"2013-06-14T08:26:03Z","timestamp":1371198363000},"page":"647-654","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":22,"title":["Prospective evaluation of irrigation fluid absorption during pure transurethral bipolar plasma vaporisation of the prostate using expired\u2010breath ethanol measurements"],"prefix":"10.1111","volume":"112","author":[{"given":"Thomas","family":"Hermanns","sequence":"first","affiliation":[{"name":"Department of Urology University Hospital, University of Z\u00fcrich Z\u00fcrich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian D.","family":"Fankhauser","sequence":"additional","affiliation":[{"name":"Department of Urology University Hospital, University of Z\u00fcrich Z\u00fcrich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lukas J.","family":"Hefermehl","sequence":"additional","affiliation":[{"name":"Department of Urology University Hospital, University of Z\u00fcrich Z\u00fcrich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benedikt","family":"Kranzb\u00fchler","sequence":"additional","affiliation":[{"name":"Department of Urology University Hospital, University of Z\u00fcrich Z\u00fcrich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lih\u2010Ming","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology Division of Urology University of Toronto, Princess Margaret Hospital Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janine C.","family":"Capol","sequence":"additional","affiliation":[{"name":"Institute of Anaesthesiology University Hospital, University of Z\u00fcrich Z\u00fcrich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthias","family":"Zimmermann","sequence":"additional","affiliation":[{"name":"Department of Urology University Hospital, University of Z\u00fcrich Z\u00fcrich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tullio","family":"Sulser","sequence":"additional","affiliation":[{"name":"Department of Urology University Hospital, University of Z\u00fcrich Z\u00fcrich Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"M\u00fcller","sequence":"additional","affiliation":[{"name":"Department of Urology University Hospital, University of Z\u00fcrich Z\u00fcrich 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