{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T07:25:45Z","timestamp":1774509945730,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2013,7,26]],"date-time":"2013-07-26T00:00:00Z","timestamp":1374796800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/3.0\/"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2013,12]]},"abstract":"\n Objective<\/jats:title>\n \n \n \n \n To evaluate the risk of different in\u2010hospital complications for patients undergoing a radical cystectomy (\n RC<\/jats:styled-content>\n ), as limited nationwide population data on short\u2010 and long\u2010term complications after\n RC<\/jats:styled-content>\n is available, despite it being the standard treatment for localised muscle\u2010invasive urinary bladder cancer (\n UBC<\/jats:styled-content>\n ).\n <\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>\n \n Patients and Methods<\/jats:title>\n \n \n \n \n In all, 7608 persons underwent a\n RC<\/jats:styled-content>\n after\n UBC<\/jats:styled-content>\n diagnosis, as registered in the\n S<\/jats:styled-content>\n wedish\n N<\/jats:styled-content>\n ational\n P<\/jats:styled-content>\n atient\n R<\/jats:styled-content>\n egister between 1964 and 2008.\n <\/jats:p>\n <\/jats:list-item>\n \n \n We estimated the frequency and incidences and calculated hazard ratios (\n HR<\/jats:styled-content>\n ) and 95% confidence intervals (\n CI<\/jats:styled-content>\n ) using multivariate\n C<\/jats:styled-content>\n ox proportional hazards models.\n <\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n \n \n Urinary tract infection\/septicaemia was the most common complication following radical cystectomy, with an incidence of 90.4 per 1,000 person years.<\/jats:p>\n <\/jats:list-item>\n \n \n There was a higher risk of urinary tract infection among patients who had a continent cutaneous reservoir (\n HR<\/jats:styled-content>\n : 1.11 (0.94\u20131.30) or orthotopic neobladder 1.21 (1.05\u20131.39) than among those with ileal conduit.\n <\/jats:p>\n <\/jats:list-item>\n \n Similarly, continent cutaneous reservoir and orthotopic neobladder were associated with increased risks for wound and abdominal wall hernias, stones in the urinary tract, hydronephrosis and nephrostomy tube treatment, and kidney failure.<\/jats:p>\n <\/jats:list-item>\n \n \n In contrast, risk of bowel obstruction was lower among those with orthotopic neobladder than those with ileal conduit (\n HR<\/jats:styled-content>\n : 0.64 (0.50\u20130.81)) and those with continent cutaneous reservoir (\n HR<\/jats:styled-content>\n : 0.92 (0.73\u20131.16).\n <\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n \n \n \n In\u2010hospital complications after\n RC<\/jats:styled-content>\n are numerous and continue to accumulate for many years after surgery, indicating the need for life\u2010long follow\u2010up of these patients.\n <\/jats:p>\n <\/jats:list-item>\n \n Comparison between different types of diversion should, however, be made with care because of potential confounding by indication.<\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/bju.12239","type":"journal-article","created":{"date-parts":[[2013,7,26]],"date-time":"2013-07-26T22:38:52Z","timestamp":1374878332000},"page":"1113-1120","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":87,"title":["Risk of in\u2010hospital complications after radical cystectomy for urinary bladder carcinoma: population\u2010based follow\u2010up study of 7608 patients"],"prefix":"10.1111","volume":"112","author":[{"given":"Mieke","family":"van Hemelrijck","sequence":"first","affiliation":[{"name":"Division of Cancer Studies Cancer Epidemiology Group School of Medicine King's College London London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Thorstenson","sequence":"additional","affiliation":[{"name":"Department of Molecular Medicine and Surgery Karolinska Institute Stockholm Sweden"},{"name":"Department of Surgery Section of Urology Capio S:t G\u00f6rans Hospital Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip","family":"Smith","sequence":"additional","affiliation":[{"name":"Surgical Department Danderyd Hospital Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Adolfsson","sequence":"additional","affiliation":[{"name":"CLINTEC Department Karolinska Institute Stockholm Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olof","family":"Akre","sequence":"additional","affiliation":[{"name":"Clinical Epidemiology Unit Department of Medicine (Solna) Karolinska Institute Stockholm 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