{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T00:19:10Z","timestamp":1768436350766,"version":"3.49.0"},"reference-count":36,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,12,13]],"date-time":"2013-12-13T00:00:00Z","timestamp":1386892800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2014,1]]},"abstract":"\n Objective<\/jats:title>\n \n \n \n To determine the overall efficacy and predictors of success of the penile preputial flap in the management of complex urethral strictures >2.5\u2009cm in length.<\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>\n \n Patients and Methods<\/jats:title>\n \n \n \n \n We performed a retrospective and prospective study of 58 patients undergoing single\u2010stage penile preputial flap urethroplasty for complex long\u2010segment urethral strictures, without lichen sclerosus, repaired between\n M<\/jats:styled-content>\n ay 2005 and\n A<\/jats:styled-content>\n pril 2012 at our institution.\n <\/jats:p>\n <\/jats:list-item>\n \n For obvious reasons circumcised patients were excluded from the study.<\/jats:p>\n <\/jats:list-item>\n \n Results were assessed by univariate analysis of various patient characteristics, preoperative and postoperative patient satisfaction (based on symptoms), and urethral ultrasonography, retrograde urethrography and uroflowmetry.<\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n \n \n The median (range) follow\u2010up was 42 (6\u201390) months, the median (range) intra\u2010operative stricture length was 48.5 (26\u201385) mm and the median (range) operating time was 90 (85\u2013125) min.<\/jats:p>\n <\/jats:list-item>\n \n A total of 87.93% of patients had a satisfactory outcome, with an overall success rate of 81.03%.<\/jats:p>\n <\/jats:list-item>\n \n \n Diabetes mellitus (relative risk [\n RR<\/jats:styled-content>\n ] 5.21, confidence interval [\n CI<\/jats:styled-content>\n ] 2.31\u201364.68,\n P<\/jats:italic>\n = 0.003) and smoking (\n RR<\/jats:styled-content>\n 4.19,\n CI<\/jats:styled-content>\n 1.54\u2013 45.0,\n P<\/jats:italic>\n = 0.01) were predictors of failure, while postinfective aetiology (\n RR<\/jats:styled-content>\n 2.19), panurethral stricture (\n RR<\/jats:styled-content>\n 2.73), stricture length >70\u2009mm (\n RR<\/jats:styled-content>\n 3.25), previous urethroplasty (\n RR<\/jats:styled-content>\n 2.4) and severe peri\u2010urethral fibrosis (\n RR<\/jats:styled-content>\n 2.37) were also associated with a higher risk of failure.\n <\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n \n \n A urologist should try to gain experience of all the methods of urethroplasty as the techniques may vary according to the circumstances.<\/jats:p>\n <\/jats:list-item>\n \n Single\u2010stage preputial skin flap urethroplasty, in experienced and expert hands, has results equivalent to all other methods of urethroplasty in complex urethral strictures.<\/jats:p>\n <\/jats:list-item>\n \n We prefer this technique in this part of the world where buccal mucosa cannot be used because of dyskeratotic changes as a result of consumption of gutkha, tobacco, pan masala, betel nut.<\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/bju.12361","type":"journal-article","created":{"date-parts":[[2013,7,9]],"date-time":"2013-07-09T04:46:42Z","timestamp":1373345202000},"page":"120-126","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Single\u2010stage preputial skin flap urethroplasty for long\u2010segment urethral strictures: evaluation and determinants of success"],"prefix":"10.1111","volume":"113","author":[{"given":"Raj Kumar","family":"Mathur","sequence":"first","affiliation":[{"name":"Department of Surgery Mahatma Gandhi Memorial Medical College and Maharaja Yashwant Rao Hospital Indore India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milesh","family":"Nagar","sequence":"additional","affiliation":[{"name":"Department of Surgery Mahatma Gandhi Memorial Medical College and Maharaja Yashwant Rao Hospital Indore India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahul","family":"Mathur","sequence":"additional","affiliation":[{"name":"Department of Surgery Mahatma Gandhi Memorial Medical College and Maharaja Yashwant Rao Hospital Indore India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fareed","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Surgery Mahatma Gandhi Memorial Medical College and Maharaja Yashwant Rao Hospital Indore India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chaitanya","family":"Deshmukh","sequence":"additional","affiliation":[{"name":"Department of Surgery Mahatma Gandhi Memorial Medical College and Maharaja Yashwant Rao Hospital Indore India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nilesh","family":"Guru","sequence":"additional","affiliation":[{"name":"Department of Surgery Mahatma Gandhi Memorial Medical College and Maharaja Yashwant Rao Hospital Indore India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,12,13]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2007.01.033"},{"key":"e_1_2_8_3_1","first-page":"3","article-title":"Reconstruction of the male urethra in strictures: application of the buried intact epithelium 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