{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T06:13:18Z","timestamp":1769926398741,"version":"3.49.0"},"reference-count":18,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,1,13]],"date-time":"2014-01-13T00:00:00Z","timestamp":1389571200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>\n                            To examine the development of recurrent urinary tract infections (\n                            <jats:styled-content style=\"fixed-case\">UTIs<\/jats:styled-content>\n                            ) in boys who have undergone hypospadias repair.\n                          <\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>\n                            We retrospectively reviewed the records of all boys who had recurrent\n                            <jats:styled-content style=\"fixed-case\">UTIs<\/jats:styled-content>\n                            after primary or redo tubularized incised plate (\n                            <jats:styled-content style=\"fixed-case\">TIP<\/jats:styled-content>\n                            ) or transverse island flap (\n                            <jats:styled-content style=\"fixed-case\">TVIF<\/jats:styled-content>\n                            ) repairs, between 1998 and 2009.\n                          <\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>Data on age, operating details, postoperative complications and imaging studies were collected.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>\n                            We attempted to identify risk factors for recurrent\n                            <jats:styled-content style=\"fixed-case\">UTIs<\/jats:styled-content>\n                            after hypospadias repair.\n                          <\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>\n                            During the study period, 43\/2249 boys (1.91%) were diagnosed with recurrent\n                            <jats:styled-content style=\"fixed-case\">UTIs<\/jats:styled-content>\n                            after hypospadias repair. The boys' mean (range) age at repair was 14 (6\u201324) months and the median (range) follow\u2010up was 6.5 (1.5\u201311) years.\n                          <\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>\n                            Primary\n                            <jats:styled-content style=\"fixed-case\">TIP<\/jats:styled-content>\n                            and\n                            <jats:styled-content style=\"fixed-case\">TVIF<\/jats:styled-content>\n                            were performed in 47% (20\/43) and 35% (15\/43) of the boys, respectively. Redo surgeries were performed in 18% of the boys (8\/43). The initial meatal location was proximal in all\n                            <jats:styled-content style=\"fixed-case\">TVIF<\/jats:styled-content>\n                            and redo repairs, and in one of the\n                            <jats:styled-content style=\"fixed-case\">TIP<\/jats:styled-content>\n                            repairs.\n                          <\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>\n                            Postoperative voiding cysto\u2010urethrography, ultrasonography and dimercapto\u2010succinic acid (\n                            <jats:styled-content style=\"fixed-case\">DMSA<\/jats:styled-content>\n                            ) scans were performed in 58% (25\/43), 90% (39\/43) and 19% (8\/43) of the boys, respectively. Abnormalities were noted.\n                          <\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>\n                            Of those boys who underwent a\n                            <jats:styled-content style=\"fixed-case\">TVIF<\/jats:styled-content>\n                            repair, urethral diverticula were seen in 47% (7\/15) and urethral fistulae were also seen in 47% (7\/15). Conversely, in those who had a\n                            <jats:styled-content style=\"fixed-case\">TIP<\/jats:styled-content>\n                            repair, an elevated\n                            <jats:styled-content style=\"fixed-case\">PVR<\/jats:styled-content>\n                            and vesico\u2010ureteric reflux were more common; they were found in 40% (8\/20) and 50% (10\/20) of patients, respectively.\n                          <\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>\n                            The pathophysiology of recurrent\n                            <jats:styled-content style=\"fixed-case\">UTI<\/jats:styled-content>\n                            is multifactorial, but postoperative complications seem to vary with type of procedure.\n                          <\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>\n                            Recurrent\n                            <jats:styled-content style=\"fixed-case\">UTIs<\/jats:styled-content>\n                            after hypospadias surgery should prompt a specific assessment for potentially functionally relevant and correctable anatomical abnormalities.\n                          <\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.12387","type":"journal-article","created":{"date-parts":[[2013,7,25]],"date-time":"2013-07-25T13:23:39Z","timestamp":1374758619000},"page":"304-308","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Urinary tract abnormalities in boys with recurrent urinary tract infections after hypospadias repair"],"prefix":"10.1111","volume":"113","author":[{"given":"Elias","family":"Wehbi","sequence":"first","affiliation":[{"name":"The Hospital for Sick Children University of Toronto  Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Premal","family":"Patel","sequence":"additional","affiliation":[{"name":"The Department of Medicine The University of Calgary  Calgary AB Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niki","family":"Kanaroglou","sequence":"additional","affiliation":[{"name":"The Hospital for Sick Children University of Toronto  Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephanie","family":"Tam","sequence":"additional","affiliation":[{"name":"The Division of Urology East York Hospital  Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bryce","family":"Weber","sequence":"additional","affiliation":[{"name":"The Division of Urology The University of Calgary  Calgary AB Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armando","family":"Lorenzo","sequence":"additional","affiliation":[{"name":"The Hospital for Sick Children University of Toronto  Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joao Luiz Pippi","family":"Salle","sequence":"additional","affiliation":[{"name":"The Hospital for Sick Children University of Toronto  Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Darius","family":"Bagli","sequence":"additional","affiliation":[{"name":"The Hospital for Sick Children University of Toronto  Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Koyle","sequence":"additional","affiliation":[{"name":"The Hospital for Sick Children University of Toronto  Toronto ON Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walid A.","family":"Farhat","sequence":"additional","affiliation":[{"name":"The Hospital for Sick Children University of Toronto  Toronto ON 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