{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:03:09Z","timestamp":1762506189910,"version":"build-2065373602"},"reference-count":37,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2013,12,16]],"date-time":"2013-12-16T00:00:00Z","timestamp":1387152000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2014,10]]},"abstract":"\n Objective<\/jats:title>\n \n \n \n \n To examine the extirpative quality of an open radical prostatectomy (\n RP<\/jats:styled-content>\n ) technique by first categorising and mapping all intraprostatic incisions into benign tissue and then determining a cumulative technical error rate given by all intraprostatic incisions into benign and malignant tissue.\n <\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>\n \n Patients and Methods<\/jats:title>\n \n \n \n \n We performed a retrospective review of prospectively collected data relating to 1065 men with clinically localised prostate cancer who underwent open retropubic\n RP<\/jats:styled-content>\n (70.6% nerve\u2010sparing surgery [\n NSS<\/jats:styled-content>\n ]) by a single surgeon (\n J<\/jats:styled-content>\n anuary 2005 to\n D<\/jats:styled-content>\n ecember 2011).\n <\/jats:p>\n <\/jats:list-item>\n \n \n We recorded all intraprostatic incisions: (i) iatrogenic positive surgical margins (\n PSMs<\/jats:styled-content>\n ), (ii) deep or superficial benign capsular incisions (\n BCIs<\/jats:styled-content>\n ), (iii) incisions into benign prostate glands at the prostate apex or bladder neck (benign glandular tissue incisions [\n BGTIs<\/jats:styled-content>\n ]), and determined incision location, length and nature (solitary\/multiple).\n <\/jats:p>\n <\/jats:list-item>\n \n \n We evaluated: (i) associations between benign incisions,\n NSS<\/jats:styled-content>\n and\n PSMs<\/jats:styled-content>\n , (ii) significant predictors for\n PSM<\/jats:styled-content>\n risk by multivariate analysis, (iii) postoperative biochemical recurrence (\n BCR<\/jats:styled-content>\n )\u2010free survival (\n K<\/jats:styled-content>\n aplan\u2013\n M<\/jats:styled-content>\n eier method).\n <\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n \n \n \n Intraprostatic incision rates were 2.3%\n pT2 PSMs<\/jats:styled-content>\n , 6.0%\n BCIs<\/jats:styled-content>\n and 5.4%\n BGTIs<\/jats:styled-content>\n . There were slight variations in rate over time and with\n NSS<\/jats:styled-content>\n technique. Benign incisions were located as follows: 46.8% right posterolateral, 37.5% left posterolateral, and 15.7% bilateral for\n BCIs<\/jats:styled-content>\n ; 58.6% bladder neck and 41.4% apical for\n BGTIs<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:list-item>\n \n \n The median (range) incision length, for solitary and multiple incisions respectively, was 4 (1\u201313) and 9 (2\u201325) mm for\n BCIs<\/jats:styled-content>\n and 1 (1\u20135) and 2 (2\u20136) mm for\n BGTIs<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:list-item>\n \n \n BCI<\/jats:styled-content>\n rate, but not\n BGTI<\/jats:styled-content>\n rate, was significantly associated with\n NSS<\/jats:styled-content>\n (\n P<\/jats:italic>\n = 0.004) and\n PSM<\/jats:styled-content>\n (\n P<\/jats:italic>\n = 0.005), and increased\n PSM<\/jats:styled-content>\n risk 3.6\u2010fold.\n <\/jats:p>\n <\/jats:list-item>\n \n \n A\n PSM<\/jats:styled-content>\n increased\n BCR<\/jats:styled-content>\n risk two\u2010fold (odds ratio 2.078, 95% confidence interval 1.383\u20133.122).\n <\/jats:p>\n <\/jats:list-item>\n \n \n BCR<\/jats:styled-content>\n \u2010free survival decreased significantly even for short\n PSMs<\/jats:styled-content>\n (<1\u2009mm; P < 0.001).\n <\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n \n \n \n Although the\n pT2 PSM<\/jats:styled-content>\n rate was low (2.3%), the cumulative technical error rate (patients with at least one\n pT2 PSM<\/jats:styled-content>\n ,\n BCI<\/jats:styled-content>\n or\n BGTI<\/jats:styled-content>\n ) was five\u2010fold higher (12.5%).\n <\/jats:p>\n <\/jats:list-item>\n \n Categorising and mapping intraprostatic incisions is a tool surgeons can use in self\u2010audits to identify areas of potential improvement, reduce errors, and improve surgical skills.<\/jats:p>\n <\/jats:list-item>\n <\/jats:list>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/bju.12467","type":"journal-article","created":{"date-parts":[[2013,10,11]],"date-time":"2013-10-11T18:03:11Z","timestamp":1381514591000},"page":"522-531","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Assessing the extirpative quality of a radical prostatectomy technique: categorisation and mapping of technical errors"],"prefix":"10.1111","volume":"114","author":[{"given":"Christian","family":"Barr\u00e9","sequence":"first","affiliation":[{"name":"Department of Urology Jules Verne Clinic Nantes France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthieu","family":"Thoulouzan","sequence":"additional","affiliation":[{"name":"Department of Urology Rangueil University Hospital Toulouse France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Genevi\u00e8ve","family":"Aillet","sequence":"additional","affiliation":[{"name":"Institute of Histo\u2010Pathology Nantes France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean\u2010Michel","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics UMR 892 University Hospital Nantes France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,12,16]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000169475.00949.78"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2005.06.108"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2008.09.051"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2010.02.017"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2009.11.039"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2010.06.018"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2012.11371.x"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/673021"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2011.10868.x"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2009.12.015"},{"key":"e_1_2_6_12_1","first-page":"923","volume-title":"Histology for Pathologists","author":"McNeal JE","year":"2007"},{"key":"e_1_2_6_13_1","first-page":"1","volume-title":"Tumors of the Prostate Gland, Seminal Vesicles, Penis, and Scrotum. AFIP Atlas of Tumor Pathology Series 4","author":"Epstein JI","year":"2001"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2006.11.057"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2009.08.138"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2012.02.029"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2011.10361.x"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(01)01336-X"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2010.155"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)62543-6"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(00)00775-5"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2004.024182"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diii.2012.01.019"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2011.10776.x"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urolonc.2011.12.011"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2007.05.159"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2007.08.042"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2009.08.088"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2010.03.090"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2010.10.059"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2012.11340.x"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2009.06.046"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2010.06.041"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2009.08953.x"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181e103bf"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2011.10572.x"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000091100.83725.51"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2008.01.107"}],"container-title":["BJU International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fbju.12467","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bju.12467","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T18:11:44Z","timestamp":1761761504000},"score":1,"resource":{"primary":{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/10.1111\/bju.12467"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12,16]]},"references-count":37,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,10]]}},"alternative-id":["10.1111\/bju.12467"],"URL":"https:\/\/doi.org\/10.1111\/bju.12467","archive":["Portico"],"relation":{},"ISSN":["1464-4096","1464-410X"],"issn-type":[{"type":"print","value":"1464-4096"},{"type":"electronic","value":"1464-410X"}],"subject":[],"published":{"date-parts":[[2013,12,16]]},"assertion":[{"value":"2013-12-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}