{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T18:13:52Z","timestamp":1761761632445,"version":"build-2065373602"},"reference-count":51,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,2,14]],"date-time":"2014-02-14T00:00:00Z","timestamp":1392336000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>\n                            To investigate the associations of a range of personal and clinical variables with bladder cancer survival in men and women in\n                            <jats:styled-content style=\"fixed-case\">NSW<\/jats:styled-content>\n                            to see if we could explain why bladder cancer survival is consistently poorer in women than in men.\n                          <\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>\n                            All 6880 cases of bladder cancers diagnosed in\n                            <jats:styled-content style=\"fixed-case\">NSW<\/jats:styled-content>\n                            between 2000 and 2008 were linked to hospital separation data and to deaths.\n                          <\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>\n                            Separate\n                            <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>\n                            ox proportional hazards regression models of hazard of bladder cancer death were constructed for those who did or did not undergo cystectomy.\n                          <\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>\n                            A total of 16% of patients with bladder cancer underwent cystectomy (16% of men and 15% of women). Women who underwent cystectomy were 26% more likely to die than men (hazard ratio [\n                            <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\n                            ] 1.26, 95% confidence interval [\n                            <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                            ] 1.00\u20131.59) after adjustment for age, stage, time from diagnosis to cystectomy, distance from treatment facility and country of birth.\n                          <\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>\n                            None of the above covariates had a material effect on the difference in hazard between women and men; however, when stratified by a history of cystitis, the adjusted hazard was 55% higher in women (\n                            <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\n                            1.55, 95%\n                            <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                            1.15\u20132.10) than in men with a history of cystitis while, in the absence of this history, there was no difference in the hazard between men and women (\n                            <jats:styled-content style=\"fixed-case\">HR<\/jats:styled-content>\n                            0.99, 95%\n                            <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                            0.57\u20131.70).\n                          <\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>\n                            This apparent modification of the effect of sex on bladder cancer outcome was not seen in patients treated only by resection: the adjusted\n                            <jats:styled-content style=\"fixed-case\">HRs<\/jats:styled-content>\n                            in women relative to men were 1.10 (95%\n                            <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                            0.92\u20131.31) in those with a history of cystitis and 1.21 (95%\n                            <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                            0.98\u20131.50) in those without.\n                          <\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>A history of haematuria did not modify appreciably the association of sex with bladder cancer outcome.<\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>Women's poorer survival from bladder cancer compared with that of men remains unexplained; however, the possibility that some factor associated with a history of cystitis may contribute to or explain the poorer outcome in women merits further investigation.<\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.12496","type":"journal-article","created":{"date-parts":[[2013,10,15]],"date-time":"2013-10-15T12:05:17Z","timestamp":1381838717000},"page":"437-448","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Investigation of poorer bladder cancer survival in women in\n                    <scp>NSW<\/scp>\n                    ,\n                    <scp>A<\/scp>\n                    ustralia: a data linkage study"],"prefix":"10.1111","volume":"113","author":[{"given":"Elizabeth","family":"Tracey","sequence":"first","affiliation":[{"name":"University of Sydney  Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hunter","family":"Watt","sequence":"additional","affiliation":[{"name":"University of Wollongong  Wollongong Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Currow","sequence":"additional","affiliation":[{"name":"The Cancer Institute New South Wales (NSW)  Sydney NSW Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane","family":"Young","sequence":"additional","affiliation":[{"name":"University of Sydney  Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruce","family":"Armstrong","sequence":"additional","affiliation":[{"name":"University of Sydney  Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,2,14]]},"reference":[{"volume-title":"Cancer in New South Wales: Incidence and Mortality 2004","year":"2006","author":"Tracey E","key":"e_1_2_7_2_1"},{"key":"e_1_2_7_3_1","unstructured":"RiesL YoungJ KeelGet\u2009al.SEER Survival Monograph: Cancer Survival among Adults: US SEER Program 1988\u20132001 Patient and Tumor Characteristics. 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