{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:03:26Z","timestamp":1762506206314,"version":"build-2065373602"},"reference-count":22,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,8,16]],"date-time":"2014-08-16T00:00:00Z","timestamp":1408147200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      To review long\u2010term oncological and functional outcomes of testicular\u2010sparing surgery (\n                      <jats:styled-content style=\"fixed-case\">TSS<\/jats:styled-content>\n                      ) in men presenting with bilateral or monorchide testicular tumours at one of five reference centres for testicular neoplasm and infertility.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>We review 25 cases of bilateral synchrone and metachrone testicular tumours treated in five academic centres between 1984 and 2013.<\/jats:p>\n                    <jats:p>\n                      Clinical, biological, ultrasonography and pathological tumour findings, overall survival (\n                      <jats:styled-content style=\"fixed-case\">OS<\/jats:styled-content>\n                      ) times, local or metastatic recurrence, pre\u2010 and postoperative hormonal profile, paternity and the need for androgen substitution were assessed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eleven patients with a bilateral synchrone tumour and 14 patients with a testicular tumour on a solitary testicle underwent a tumorectomy.<\/jats:p>\n                    <jats:p>\n                      The mean (\n                      <jats:sc>sem<\/jats:sc>\n                      ) patient age was 31.9 (1.04) years, total testosterone level was 4.5 (0.57) ng.mL and tumour size was 11.66 (1.49) mm.\n                    <\/jats:p>\n                    <jats:p>\n                      Tumour types were as follows: 11 seminoma, nine non\u2010seminomatous or mixed germ cell tumours, four\n                      <jats:styled-content style=\"fixed-case\">L<\/jats:styled-content>\n                      eydig tumours, and one hamartoma. Frozen\u2010section examination was performed in 14 patients, and matched the final pathological analysis in 11 patients.\n                    <\/jats:p>\n                    <jats:p>\n                      There was an\n                      <jats:styled-content style=\"fixed-case\">OS<\/jats:styled-content>\n                      rate of 100% and three patients (12%) presented with a local recurrence after a mean follow\u2010up of 42.7 months.\n                    <\/jats:p>\n                    <jats:p>Radical orchiectomy was performed for six patients. No patient with a preserved testicle required androgen therapy; the mean postoperative total testosterone level was 4.0\u2009ng\/mL.<\/jats:p>\n                    <jats:p>No patient remained fertile after radiation therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      <jats:styled-content style=\"fixed-case\">TSS<\/jats:styled-content>\n                      for bilateral testicular tumour is safe and effective in selected patients, and should be considered to avoid definitive androgen therapy.\n                    <\/jats:p>\n                    <jats:p>Adjuvant radiotherapy remains poorly described in the literature, leading to adjuvant treatment heterogeneity for testicular tumours.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.12549","type":"journal-article","created":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T09:51:44Z","timestamp":1383299504000},"page":"860-864","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Testicular\u2010sparing surgery for bilateral or monorchide testicular tumours: a multicenter study of long\u2010term oncological and functional results"],"prefix":"10.1111","volume":"114","author":[{"given":"Ludovic","family":"Ferretti","sequence":"first","affiliation":[{"name":"Department of Urology University Hospital Pellegrin  Bordeaux France"},{"name":"Department of Surgery HIA Robert Picque  Villenave d'Ornon France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Sargos","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy Bergonie Institut  Bordeaux France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marine","family":"Gross\u2010Goupil","sequence":"additional","affiliation":[{"name":"Department of Oncology University Hospital Saint\u2010Andr\u00e9  Bordeaux France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincent","family":"Izard","sequence":"additional","affiliation":[{"name":"Department of Urology Paris XI University Hospital  Le Kremlin\u2010Bic\u00eatre"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Herv\u00e9","family":"Wallerand","sequence":"additional","affiliation":[{"name":"Department of Urology University Hospital Pellegrin  Bordeaux France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Huyghe","sequence":"additional","affiliation":[{"name":"Department of Urology University Hospital Rangueil  Toulouse France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean\u2010Marc","family":"Rigot","sequence":"additional","affiliation":[{"name":"Andrology and Fertility Department University Hospital of Lille  Lille France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xavier","family":"Durand","sequence":"additional","affiliation":[{"name":"Department of Urology HIA of the Val\u2010De\u2010Gr\u00e2ce  Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerard","family":"Benoit","sequence":"additional","affiliation":[{"name":"Department of Urology Paris XI University Hospital  Le Kremlin\u2010Bic\u00eatre"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean\u2010Marie","family":"Ferriere","sequence":"additional","affiliation":[{"name":"Department of Urology University Hospital Pellegrin  Bordeaux France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"St\u00e9phane","family":"Droupy","sequence":"additional","affiliation":[{"name":"Department of Urology\u2010Andrology University Hospital of N\u00eemes N\u00eemes\u2010Montpellier University  N\u00eemes France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,8,16]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2004.03.022"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)66984-X"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2008.08.474"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-8049(99)00123-9"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2004.05.006"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2007.12.024"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1166-7087(07)74779-6"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2007.05.077"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)67534-7"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)65526-7"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2010.01.014"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(01)01483-3"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000152532.34475.4e"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canrad.2013.03.005"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2008.08016.x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008213515649"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000092066.01699.90"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000134892.10525.39"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0302-2838(03)00316-6"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2008.11.057"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6600771"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0302-2838(02)00274-9"}],"container-title":["BJU International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fbju.12549","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bju.12549","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T10:28:07Z","timestamp":1761733687000},"score":1,"resource":{"primary":{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/10.1111\/bju.12549"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8,16]]},"references-count":22,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["10.1111\/bju.12549"],"URL":"https:\/\/doi.org\/10.1111\/bju.12549","archive":["Portico"],"relation":{},"ISSN":["1464-4096","1464-410X"],"issn-type":[{"type":"print","value":"1464-4096"},{"type":"electronic","value":"1464-410X"}],"subject":[],"published":{"date-parts":[[2014,8,16]]},"assertion":[{"value":"2014-08-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}