{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T17:39:04Z","timestamp":1787765944211,"version":"build-2784847793"},"reference-count":30,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,4,9]],"date-time":"2014-04-09T00:00:00Z","timestamp":1397001600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2014,5]]},"abstract":"\n Objective<\/jats:title>\n \n To determine the peri\u2010operative outcomes of men undergoing salvage robot\u2010assisted prostatectomy (\n RARP<\/jats:styled-content>\n ) and to examine the complications, functional consequences and need for additional treatments after salvage\n RARP<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Patients and Methods<\/jats:title>\n \n At total of 51 consecutive patients underwent salvage\n RARP<\/jats:styled-content>\n after previous failed local therapy. Biochemical recurrence (\n BCR<\/jats:styled-content>\n ) was defined as two postoperative\n PSA<\/jats:styled-content>\n measurements \u22650.2\u2009ng\/mL. Complications at any time postoperatively were recorded prospectively using a modified\n C<\/jats:styled-content>\n lavien system. The\n K<\/jats:styled-content>\n aplan\u2013\n M<\/jats:styled-content>\n eier method was used for survival estimation, and regression models were used to identify the predictors of\n BCR<\/jats:styled-content>\n or progression\u2010free survival (\n PFS<\/jats:styled-content>\n ) and complications.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The median age at salvage\n RARP<\/jats:styled-content>\n was 68 years and a median of 68 months had elapsed from the time of primary treatment. The median follow\u2010up was 36 months. The median operation duration was 179\u2009min with a median estimated blood loss of 175\u2009mL. In all, 50% of patients had pathological stage 3 disease and positive surgical margins were found in 31% of patients. The estimated 3\u2010year\n BCR<\/jats:styled-content>\n \u2010free or\n PFS<\/jats:styled-content>\n was 57%. The overall complication rate was 47%, with a 35% major complication rate (\n G<\/jats:styled-content>\n rade\n III<\/jats:styled-content>\n \u2013\n V<\/jats:styled-content>\n ). Potency was maintained in 23% of preoperatively potent patients and 45% of all patients regained urinary control. No clinical variables were predictive of major complications, but all patients with postoperative bladder neck contracture were incontinent. A higher\n PSA<\/jats:styled-content>\n level and extracapsular extension were significantly associated with\n BCR<\/jats:styled-content>\n or progression (\n P<\/jats:italic>\n < 0.01).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Salvage\n RARP<\/jats:styled-content>\n provides oncological control with potential avoidance of systemic non\u2010curative therapy. Complication, incontinence and erectile dysfunction rates are significant but frequently correctable. This reinforces the need for proper patient counselling and selection.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/bju.12595","type":"journal-article","created":{"date-parts":[[2013,12,6]],"date-time":"2013-12-06T06:50:46Z","timestamp":1386312646000},"page":"769-776","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":65,"title":["Complications and outcomes of salvage robot\u2010assisted radical prostatectomy: a single\u2010institution experience"],"prefix":"10.1111","volume":"113","author":[{"given":"Bertram","family":"Yuh","sequence":"first","affiliation":[{"name":"City of Hope National Cancer Center, Urology Duarte CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nora","family":"Ruel","sequence":"additional","affiliation":[{"name":"City of Hope National Cancer Center, Urology Duarte CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shantel","family":"Muldrew","sequence":"additional","affiliation":[{"name":"City of Hope National Cancer Center, Urology Duarte CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa","family":"Mejia","sequence":"additional","affiliation":[{"name":"City of Hope National Cancer Center, Urology Duarte CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giacomo","family":"Novara","sequence":"additional","affiliation":[{"name":"Department of Surgical, Oncological, and Gastroenterological Sciences Urology Clinic University of Padua Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Kawachi","sequence":"additional","affiliation":[{"name":"City of Hope National Cancer Center, Urology Duarte CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Wilson","sequence":"additional","affiliation":[{"name":"City of Hope National Cancer Center, Urology Duarte CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,4,9]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"American Cancer Society. 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