{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T22:48:45Z","timestamp":1779922125127,"version":"3.53.1"},"reference-count":7,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,8,11]],"date-time":"2014-08-11T00:00:00Z","timestamp":1407715200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2014,11]]},"abstract":"\n Objectives<\/jats:title>\n To describe, step\u2010by\u2010step, our hands\u2010free technique for focal cryoablation of prostate cancer.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods<\/jats:title>\n \n After detailed discussion of its limitations and benefits, consent was obtained to perform focal cryoablation in patients with biopsy\u2010proven unilateral low\u2010 to intermediate\u2010risk prostate cancer. The procedure was performed transperineally, using a hands\u2010free technique (without an external grid template) under real\u2010time bi\u2010plane transrectal ultrasonography (\n TRUS<\/jats:styled-content>\n ) guidance, using an argon\/helium\u2010gas\u2010based third generation cryoablation system. Follow\u2010up consisted of validated questionnaires, physical examination,\n PSA<\/jats:styled-content>\n measures, multiparametric\n TRUS<\/jats:styled-content>\n and\/or magnetic resonance imaging (\n MRI<\/jats:styled-content>\n ) and mandatory biopsy.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The important steps for achieving safety, satisfactory oncological and functional outcomes included: patient selection, including\n TRUS<\/jats:styled-content>\n \/\n MRI<\/jats:styled-content>\n fusion target biopsy; thermocouple and cryoprobe placement with a hands\u2010free technique, allowing delivery in unrestricted angulations according to the prostatic contour, the course of the neurovascular bundle and the rectal wall angle; and hands\u2010free bi\u2010plane\n TRUS<\/jats:styled-content>\n probe manipulation to facilitate real\u2010time monitoring of anatomical landmarks at the ideal angle of the image plane. To achieve a lethal temperature in the known cancer area, while preserving the urinary sphincter, neurovascular bundle, urethra and rectal wall, continuous intraoperative control of the thermocouple temperatures was necessary, as were real\u2010time\n TRUS<\/jats:styled-content>\n monitoring of ice\u2010ball size, control of the energy delivered and the use of a warming urethral catheter.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n We have described step\u2010by\u2010step the focal cryoablation of prostate cancer using a hands\u2010free technique. This technique facilitates the effective delivery of cryoprobes and the intra\u2010operative real\u2010time quick manipulation of the\n TRUS<\/jats:styled-content>\n probe.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/bju.12795","type":"journal-article","created":{"date-parts":[[2014,5,6]],"date-time":"2014-05-06T23:07:03Z","timestamp":1399417623000},"page":"784-789","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Real\u2010time transrectal ultrasonography\u2010guided hands\u2010free technique for focal cryoablation of the prostate"],"prefix":"10.1111","volume":"114","author":[{"given":"Andre Luis","family":"de Castro Abreu","sequence":"first","affiliation":[{"name":"USC Institute of Urology Catherine and Joseph Aresty Department of Urology Center for Prostate Cancer Focal Therapy Keck School of Medicine University of Southern California Los Angeles CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duke","family":"Bahn","sequence":"additional","affiliation":[{"name":"Prostate Institute of America Community Memorial Hospital Ventura CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sameer","family":"Chopra","sequence":"additional","affiliation":[{"name":"USC Institute of Urology Catherine and Joseph Aresty Department of Urology Center for Prostate Cancer Focal Therapy Keck School of Medicine University of Southern California Los Angeles CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott","family":"Leslie","sequence":"additional","affiliation":[{"name":"USC Institute of Urology Catherine and Joseph Aresty Department of Urology Center for Prostate Cancer Focal Therapy Keck School of Medicine University of Southern California Los Angeles CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toru","family":"Matsugasumi","sequence":"additional","affiliation":[{"name":"USC Institute of Urology Catherine and Joseph Aresty Department of Urology Center for Prostate Cancer Focal Therapy Keck School of Medicine University of Southern California Los Angeles CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Inderbir S.","family":"Gill","sequence":"additional","affiliation":[{"name":"USC Institute of Urology Catherine and Joseph Aresty Department of Urology Center for Prostate Cancer Focal Therapy Keck School of Medicine University of Southern California Los Angeles CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osamu","family":"Ukimura","sequence":"additional","affiliation":[{"name":"USC Institute of Urology Catherine and Joseph Aresty Department of Urology Center for Prostate Cancer Focal Therapy Keck School of Medicine University of Southern California Los Angeles CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,8,11]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2008.07.108"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.12124"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.12151"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2011.10.124"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2012.03.006"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.280.11.969"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOU.0b013e328323f654"}],"container-title":["BJU International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fbju.12795","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bju.12795","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T17:26:58Z","timestamp":1761758818000},"score":1,"resource":{"primary":{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/10.1111\/bju.12795"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8,11]]},"references-count":7,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["10.1111\/bju.12795"],"URL":"https:\/\/doi.org\/10.1111\/bju.12795","archive":["Portico"],"relation":{},"ISSN":["1464-4096","1464-410X"],"issn-type":[{"value":"1464-4096","type":"print"},{"value":"1464-410X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,8,11]]},"assertion":[{"value":"2014-08-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}