{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T22:37:42Z","timestamp":1792017462521,"version":"4.4.0"},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,10,20]],"date-time":"2014-10-20T00:00:00Z","timestamp":1413763200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2015,3]]},"abstract":"\n Objective<\/jats:title>\n \n To assess the long\u2010term efficacy of polydimethylsiloxane (\n M<\/jats:styled-content>\n acroplastique\n \u00ae<\/jats:sup>\n ) injection (\n MPI<\/jats:styled-content>\n ) in the treatment of\n M<\/jats:styled-content>\n itrofanoff leakage secondary to valve incompetence.\n <\/jats:p>\n <\/jats:sec>\n \n Patients and Methods<\/jats:title>\n \n Between 1995 and 2012, the records of 24 consecutive patients who underwent\n MPI<\/jats:styled-content>\n for Mitrofanoff urinary leakage after continent cutaneous urinary diversion (\n CCUD<\/jats:styled-content>\n ) surgery were examined. All patients had a valve deemed of sufficient length (>2\u2009cm) to attempt Macroplastique coaptation. Treatment outcomes were divided into three categories based on physician assessment: success (dry), partial success (>50% reduction in incontinence pads) and failure. Success rates were assessed according to the type of reservoir and conduit channel.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The mean (range) follow\u2010up was 30\u2009(6\u201396) months. One patient had initial difficulty catheterising, and subsequently required major revision surgery. In all, 12 patients (50%) failed the treatment and subsequently underwent operative revision to the channel. Three patients (12.5%) achieved complete success; one patient had an appendix channel through native bladder and the remaining two had\n M<\/jats:styled-content>\n onti channels through colon. Nine patients (37.5%) had partial success; success rates were higher with appendix channels (four of six) and colonic reservoirs (six of seven) when compared with\n M<\/jats:styled-content>\n onti channels (eight of 18, 44%) and ileal reservoirs (zero of two). Five of the nine patients with partial success eventually required further surgical revision for deteriorating continence at a mean (range) of 41\u2009(14\u201396) months, whilst the other four have maintained sufficient continence with\n MPI<\/jats:styled-content>\n alone.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n Macroplastique bulking cured only 12.5% patients, but leakage was substantially improved in a further 37.5% allowing major surgery to be avoided or postponed in one half of the cohort. Appendix\n M<\/jats:styled-content>\n itrofanoffs do better than the\n M<\/jats:styled-content>\n onti\n M<\/jats:styled-content>\n itrofanoff, with channels through colonic segments generally doing better than those through ileal bladders.\n MPI<\/jats:styled-content>\n should be considered as a less invasive alternative to avoid or delay major reconstructive surgery.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/bju.12817","type":"journal-article","created":{"date-parts":[[2014,5,26]],"date-time":"2014-05-26T05:52:54Z","timestamp":1401083574000},"page":"461-465","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Long\u2010term efficacy of polydimethylsiloxane (\n M<\/scp>\n acroplastique\n \u00ae<\/sup>\n ) injection for\n M<\/scp>\n itrofanoff leakage after continent urinary diversion surgery"],"prefix":"10.1111","volume":"115","author":[{"given":"Antoine","family":"Kass\u2010iliyya","sequence":"first","affiliation":[{"name":"Department of Urology University College London Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tina G.","family":"Rashid","sequence":"additional","affiliation":[{"name":"Department of Urology University College London Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabella","family":"Citron","sequence":"additional","affiliation":[{"name":"Department of Urology University College London Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Foley","sequence":"additional","affiliation":[{"name":"Department of Urology Lister Hospital Stevenage UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rizwan","family":"Hamid","sequence":"additional","affiliation":[{"name":"Department of Urology University College London Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamsin J.","family":"Greenwell","sequence":"additional","affiliation":[{"name":"Department of Urology University College London Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. Julian R.","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Urology University College London Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy L.","family":"Ockrim","sequence":"additional","affiliation":[{"name":"Department of Urology University College London Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,10,20]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"297","article-title":"Trans\u2010appendicular continent cystostomy in the management of the neurogenic bladder","volume":"21","author":"Mitrofanoff P","year":"1980","journal-title":"Chir Pediatr"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2010.01.015"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1994.tb00421.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-006-0105-z"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(06)00571-4"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2008.07467.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-1591.120113"},{"issue":"2","key":"e_1_2_6_9_1","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD003881","article-title":"Periurethral injection therapy for urinary incontinence in women","author":"Pickard R","year":"2003","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-012-1825-9"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)64998-X"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-410X.2002.02676.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000111221.43756.a3"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)00185-0"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2008.03.093"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)67599-4"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-410X.2002.02561.x"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0031-1275748"},{"key":"e_1_2_6_19_1","first-page":"578","article-title":"Mitrofanoff continent urinary diversions: the opinion of 57 patients","volume":"16","author":"Chabchoud K","year":"2006","journal-title":"Prog Urol"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.3109\/08941939509016518"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(99)00098-9"}],"container-title":["BJU International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fbju.12817","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fbju.12817","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bju.12817","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T12:28:53Z","timestamp":1761740933000},"score":1,"resource":{"primary":{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/10.1111\/bju.12817"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,10,20]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,3]]}},"alternative-id":["10.1111\/bju.12817"],"URL":"https:\/\/doi.org\/10.1111\/bju.12817","archive":["Portico"],"relation":{},"ISSN":["1464-4096","1464-410X"],"issn-type":[{"value":"1464-4096","type":"print"},{"value":"1464-410X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,10,20]]},"assertion":[{"value":"2014-10-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}