{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T04:01:05Z","timestamp":1767844865473,"version":"3.49.0"},"reference-count":29,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,10,20]],"date-time":"2014-10-20T00:00:00Z","timestamp":1413763200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2015,4]]},"abstract":"\n Objective<\/jats:title>\n \n To test the hypothesis that joint hypermobility (\n JHM<\/jats:styled-content>\n ) is associated with specific urinary incontinence (\n UI<\/jats:styled-content>\n ) subtypes and uterovaginal prolapse.\n <\/jats:p>\n <\/jats:sec>\n \n Patients and Methods<\/jats:title>\n \n In all, 270 women scheduled to undergo urodynamic investigations were invited to self\u2010complete a validated five\u2010item\n JHM<\/jats:styled-content>\n questionnaire. Women underwent history taking, symptoms assessing via the King's Health Questionnaire and clinical examination using the Pelvic Organ Prolapse Quantification system. Associations between\n JHM<\/jats:styled-content>\n and pelvic floor disorders in univariate and multivariate ordinal regression were reported using odds ratios (\n OR<\/jats:styled-content>\n s) and 95% confidence intervals (\n CI<\/jats:styled-content>\n s).\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n The prevalence of\n JHM<\/jats:styled-content>\n was 31.1%.\n JHM<\/jats:styled-content>\n had a negative association with age (\n OR<\/jats:styled-content>\n 0.98\/year,\n P<\/jats:italic>\n = 0.04). There was no association between\n JHM<\/jats:styled-content>\n and either urodynamic (\n P<\/jats:italic>\n = 0.41), or symptomatic stress\n UI<\/jats:styled-content>\n (\n P<\/jats:italic>\n = 0.48). Nor was there association with detrusor overactivity or symptomatic urgency\n UI<\/jats:styled-content>\n . Multivariate ordinal regression of\n JHM<\/jats:styled-content>\n with maximum prolapse stage, adjusting for age, showed a significant relationship (\n OR<\/jats:styled-content>\n 1.26\/stage, 95%\n CI<\/jats:styled-content>\n 1.06\u20131.46,\n P<\/jats:italic>\n < 0.05).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n Although\n JHM<\/jats:styled-content>\n is highly prevalent amongst women with lower urinary tract symptoms (LUTS), there is no strong association of\n JHM<\/jats:styled-content>\n with any\n UI<\/jats:styled-content>\n subtype. There is a trend towards higher prolapse staging in women with\n JHM<\/jats:styled-content>\n , which becomes significant only after adjustment for the confounding negative association between age and\n JHM<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/bju.12823","type":"journal-article","created":{"date-parts":[[2014,6,6]],"date-time":"2014-06-06T06:58:45Z","timestamp":1402037925000},"page":"639-643","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Lack of association of joint hypermobility with urinary incontinence subtypes and pelvic organ prolapse"],"prefix":"10.1111","volume":"115","author":[{"given":"Alex","family":"Derpapas","sequence":"first","affiliation":[{"name":"Department of Urogynaecology St Mary's Hospital Imperial College Healthcare NHS Trust London Merseyside UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rufus","family":"Cartwright","sequence":"additional","affiliation":[{"name":"Institute of Reproductive and Developmental Biology Hammersmith Hospital London Merseyside UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Purnima","family":"Upadhyaya","sequence":"additional","affiliation":[{"name":"University of Liverpool Liverpool Merseyside UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alka A.","family":"Bhide","sequence":"additional","affiliation":[{"name":"Department of Urogynaecology St Mary's Hospital Imperial College Healthcare NHS Trust London Merseyside UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex G.","family":"Digesu","sequence":"additional","affiliation":[{"name":"Department of Urogynaecology St Mary's Hospital Imperial College Healthcare NHS Trust London Merseyside 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