{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T13:08:32Z","timestamp":1783688912682,"version":"3.55.0"},"reference-count":13,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,6,3]],"date-time":"2015-06-03T00:00:00Z","timestamp":1433289600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2016,3]]},"abstract":"\n Objectives<\/jats:title>\n \n To assess the accuracy of magnetic resonance imaging (\n MRI<\/jats:styled-content>\n ) in predicting invasion of the tunica albuginea (\n TA<\/jats:styled-content>\n ) and the urethra during the primary staging of penile cancer.\n <\/jats:p>\n <\/jats:sec>\n \n Patients and Methods<\/jats:title>\n \n In all, 104 consecutive patients with clinical T1\u2013T3 penile cancer had a penile\n MRI<\/jats:styled-content>\n as a part of local staging protocol. An artificial erection was induced before MRI by injecting alprostadil (prostaglandin E\n 1<\/jats:sub>\n ). Four men with poor quality\n MRI<\/jats:styled-content>\n images were excluded from the study. The preoperative\n MRI<\/jats:styled-content>\n was compared with final histology to assess its accuracy in predicting the invasion of the\n TA<\/jats:styled-content>\n and urethra.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Data of 100 patients who underwent penile\n MRI<\/jats:styled-content>\n before definitive surgery for invasive penile carcinoma were available for analysis. The mean age was 65\u00a0years and number of patients with pathological stage T1, T2 and T3 was 32, 52, and 16, respectively. The sensitivity and specificity of\n MRI<\/jats:styled-content>\n in predicting the invasion of\n TA<\/jats:styled-content>\n and urethra was 82.1% and 73.6%, and 62.5% and 82.1%, respectively. There were no\n MRI<\/jats:styled-content>\n \u2010related complications.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n This study shows that penile\n MRI<\/jats:styled-content>\n is an accurate method for assessing\n TA<\/jats:styled-content>\n invasion but is less sensitive in assessing urethral invasion. These results support the use of\n MRI<\/jats:styled-content>\n in the local staging of penile cancer.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/bju.13041","type":"journal-article","created":{"date-parts":[[2015,1,20]],"date-time":"2015-01-20T02:34:16Z","timestamp":1421721256000},"page":"439-443","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["The accuracy of magnetic resonance imaging (\n MRI<\/scp>\n ) in predicting the invasion of the tunica albuginea and the urethra during the primary staging of penile cancer"],"prefix":"10.1111","volume":"117","author":[{"given":"Vishwanath","family":"Hanchanale","sequence":"first","affiliation":[{"name":"Pyrah Department of Urology St James's University Hospital Leeds Teaching Hospitals NHS Trust Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lehana","family":"Yeo","sequence":"additional","affiliation":[{"name":"Pyrah Department of Urology St James's University Hospital Leeds Teaching Hospitals NHS Trust Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nawraj","family":"Subedi","sequence":"additional","affiliation":[{"name":"Department of Radiology St James's University Hospital Leeds Teaching Hospitals NHS Trust Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Radiology St James's University Hospital Leeds Teaching Hospitals NHS Trust Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tze","family":"Wah","sequence":"additional","affiliation":[{"name":"Department of Radiology St James's University Hospital Leeds Teaching Hospitals NHS Trust Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Harnden","sequence":"additional","affiliation":[{"name":"Department of Pathology St James's University Hospital Leeds Teaching Hospitals NHS Trust Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Selina","family":"Bhattarai","sequence":"additional","affiliation":[{"name":"Department of Pathology St James's University Hospital Leeds Teaching Hospitals NHS Trust Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sameer","family":"Chilka","sequence":"additional","affiliation":[{"name":"Department of Pathology St James's University Hospital Leeds Teaching Hospitals NHS Trust Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Eardley","sequence":"additional","affiliation":[{"name":"Pyrah Department of Urology St James's University Hospital Leeds Teaching Hospitals NHS Trust Leeds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,6,3]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urolonc.2006.08.029"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2005.05769.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S1569-9056(08)60162-1","article-title":"PT2 penile squamous cell carcinomas: cavernosus vs. spongiosus invasion","volume":"7","author":"Rees R","year":"2008","journal-title":"Eur Urol Suppl"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2012.05.012"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2006.11.014"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)63942-0"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2011.05.084"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2007.02.038"},{"key":"e_1_2_6_10_1","unstructured":"PizzocaroG AlgabaF SolsonaEet\u00a0al.Guidelines on Penile Cancer European Association of Urology 2012. 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