{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:30:39Z","timestamp":1761863439401,"version":"build-2065373602"},"reference-count":19,"publisher":"Wiley","issue":"S3","license":[{"start":{"date-parts":[[2015,7,21]],"date-time":"2015-07-21T00:00:00Z","timestamp":1437436800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      To describe the natural history and quality of life (\n                      <jats:styled-content style=\"fixed-case\">QoL<\/jats:styled-content>\n                      ) in patients with cystine urolithiasis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>\n                      A cohort study was carried out involving participants recruited from a single surgeon's case mix. Patients with cystinuria and related urolithiasis were invited to complete a questionnaire involving demographic information, use of medical treatment, surgical interventions and the 36\u2010item short\u2010form 36\u2010item short\u2010form health survey (\n                      <jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content>\n                      \u201036).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In all, 14 patients completed the survey. The\n                      <jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content>\n                      \u201036 survey showed lower\n                      <jats:styled-content style=\"fixed-case\">QoL<\/jats:styled-content>\n                      than the general public in seven of eight domains. The mean interventional rate in patients with cystinuria was 10.6 procedures per patient. Most patients reported previous use of\n                      <jats:sc>d<\/jats:sc>\n                      \u2010penicillamine and urinary alkalinisation medications, with most ceasing due to side\u2010effects or lack of perceived efficacy.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Cystinuria is associated with a high rate of surgical intervention and lower\n                      <jats:styled-content style=\"fixed-case\">QoL<\/jats:styled-content>\n                      than the general public. Individuals with this condition report that medical management is either ineffective or poorly tolerated. There is a need for further improvements in medical management of cystinuria, to reduce the rate of operative intervention.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.13169","type":"journal-article","created":{"date-parts":[[2015,7,21]],"date-time":"2015-07-21T05:17:55Z","timestamp":1437455875000},"page":"31-35","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Natural history and quality of life in patients with cystine urolithiasis: a single centre study"],"prefix":"10.1111","volume":"116","author":[{"given":"Justin M.","family":"Parr","sequence":"first","affiliation":[{"name":"School of Medicine The University of Queensland  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Devang","family":"Desai","sequence":"additional","affiliation":[{"name":"School of Medicine The University of Queensland  Brisbane Queensland Australia"},{"name":"Department of Urology Mater Hospital Brisbane  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Winkle","sequence":"additional","affiliation":[{"name":"School of Medicine The University of Queensland  Brisbane Queensland Australia"},{"name":"Department of Urology Mater Hospital Brisbane  Brisbane Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,7,21]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2010.11.073"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365599009180859"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eeus.2006.06.001"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.12383"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)67633-1"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrurol.2014.51"},{"key":"e_1_2_7_8_1","first-page":"228","article-title":"Cystine nephrolithiasis","volume":"3","author":"Fattah H","year":"2014","journal-title":"Transl Androl Urol"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semnephrol.2008.01.011"},{"key":"e_1_2_7_10_1","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1001\/archinte.1987.00370080045011","article-title":"Captopril reduces urinary cystine excretion in cystinuria","volume":"147","author":"Sloand JA","year":"1987","journal-title":"Arch Intern Med"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)67256-2"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8529(02)00033-6"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)64037-2"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000181817.89703.66"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1989.03430070055030"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199206000-00002"},{"volume-title":"4399.0 \u2013 National Health Survey: SF36 Population Norms, Australia, 1995","year":"1995","author":"Australian Bureau of Statistics","key":"e_1_2_7_17_1"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2012.04.015"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8529(02)00054-3"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.12708"}],"container-title":["BJU International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fbju.13169","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bju.13169","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T12:01:00Z","timestamp":1761739260000},"score":1,"resource":{"primary":{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/10.1111\/bju.13169"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7,21]]},"references-count":19,"journal-issue":{"issue":"S3","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["10.1111\/bju.13169"],"URL":"https:\/\/doi.org\/10.1111\/bju.13169","archive":["Portico"],"relation":{},"ISSN":["1464-4096","1464-410X"],"issn-type":[{"type":"print","value":"1464-4096"},{"type":"electronic","value":"1464-410X"}],"subject":[],"published":{"date-parts":[[2015,7,21]]},"assertion":[{"value":"2015-07-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}