{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T23:35:43Z","timestamp":1789688143971,"version":"4.0.1"},"reference-count":33,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,2,23]],"date-time":"2016-02-23T00:00:00Z","timestamp":1456185600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["581510"],"award-info":[{"award-number":["581510"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      To investigate in a prospective, observational study whether transperineal prostate biopsy (\n                      <jats:styled-content style=\"fixed-case\">TP<\/jats:styled-content>\n                      bx) results in patient\u2010reported quality\u2010of\u2010life (QoL) changes from baseline in the first 3\u2010months after\n                      <jats:styled-content style=\"fixed-case\">TP<\/jats:styled-content>\n                      bx.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and methods<\/jats:title>\n                    <jats:p>\n                      Consenting patients completed the 26\u2010item Expanded Prostate cancer Index Composite (\n                      <jats:styled-content style=\"fixed-case\">EPIC<\/jats:styled-content>\n                      \u201026), the Sexual Health Inventory for Men, the International Prostate Symptom Score, the Generalised Anxiety Disorder seven\u2010item scale, the Patient Health Questionnaire nine\u2010item scale, and a global question about willingness to have a repeat\n                      <jats:styled-content style=\"fixed-case\">TP<\/jats:styled-content>\n                      bx in a years' time. The instruments were scored using published scoring methods. Wilcoxon signed\u2013rank tests and Mann\u2013Whitney\n                      <jats:italic>U<\/jats:italic>\n                      \u2010tests were used to investigate statistically significant differences. Clinically significant differences were also investigated defined by published minimal important differences for the\n                      <jats:styled-content style=\"fixed-case\">EPIC<\/jats:styled-content>\n                      \u201026 and changes in established categorical groups for the other instruments.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In all, 53 patients consented to participate and completed the baseline questionnaire, in addition to at least one of the 1\u2010 or 3\u2010month follow\u2010up questionnaires. We found that most patients having a\n                      <jats:styled-content style=\"fixed-case\">TP<\/jats:styled-content>\n                      bx had no clinically significant change in QoL in the first 3 months after\n                      <jats:styled-content style=\"fixed-case\">TP<\/jats:styled-content>\n                      bx. However, 24% had clinically worse urinary function and 18% had worse sexual function at 1 month. At 3 months, 3% of patients had clinically worse urinary function and 25% continued to have worse sexual function compared with baseline. Patients who were subsequently diagnosed with cancer based on the results of the\n                      <jats:styled-content style=\"fixed-case\">TP<\/jats:styled-content>\n                      bx, had statistically significantly reduced QoL for the\n                      <jats:styled-content style=\"fixed-case\">EPIC<\/jats:styled-content>\n                      \u201026 urinary scales and reduced improvements in scores on the psychological scales at the 1\u2010month follow\u2010up compared with those who were not diagnosed with cancer.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Most patients having a\n                      <jats:styled-content style=\"fixed-case\">TP<\/jats:styled-content>\n                      bx had no clinically significant change in QoL in the first 3 months after\n                      <jats:styled-content style=\"fixed-case\">TP<\/jats:styled-content>\n                      bx. However, patients should be advised that a quarter may have clinically worse urinary function and nearly 20% have clinically worse sexual function in the first month, and that sexual function deficits may continue up to 3 months. The results of this study provide a resource that the clinician can use when discussing\n                      <jats:styled-content style=\"fixed-case\">TP<\/jats:styled-content>\n                      bx with patients.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.13413","type":"journal-article","created":{"date-parts":[[2016,1,18]],"date-time":"2016-01-18T09:33:45Z","timestamp":1453109625000},"page":"60-67","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["A prospective study of the short\u2010term quality\u2010of\u2010life outcomes of patients undergoing transperineal prostate biopsy"],"prefix":"10.1111","volume":"118","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5224-3106","authenticated-orcid":false,"given":"Adam S.","family":"Dowrick","sequence":"first","affiliation":[{"name":"Department of Cancer Research and Molecular Medicine Norwegian University of Science and Technology Trondheim Norway"},{"name":"Department of Urology Royal Melbourne Hospital Melbourne Vic. Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Addie C.","family":"Wootten","sequence":"additional","affiliation":[{"name":"Department of Urology Royal Melbourne Hospital Melbourne Vic. Australia"},{"name":"Australian Prostate Cancer Research Centre Epworth Melbourne Vic. Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Howard","sequence":"additional","affiliation":[{"name":"Australian Prostate Cancer Research Centre Epworth Melbourne Vic. Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin S.","family":"Peters","sequence":"additional","affiliation":[{"name":"Department of Urology Royal Melbourne Hospital Melbourne Vic. Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Declan G.","family":"Murphy","sequence":"additional","affiliation":[{"name":"Department of Urology Royal Melbourne Hospital Melbourne Vic. Australia"},{"name":"Peter MacCallum Cancer Centre Division of Cancer Surgery University of Melbourne Melbourne Vic. Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,2,23]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)67453-8"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.12282"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.12536"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11934-012-0277-6"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)65543-7"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005392-200102000-00023"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2013.05.049"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.45.4801"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.13002"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-015-0729-z"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1197\/aemj.10.3.261"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2014.07.111"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.6036"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrurol.2015.236"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.13049"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21278"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.12765"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.12132"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2010.01.027"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2014.08.044"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijir.3900472"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)66975-1"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.10.1092"},{"key":"e_1_2_7_25_1","volume-title":"Diagnostic and Statistical Manual of Mental Disorders: DSM\u2010IV","author":"American Psychiatric Association","year":"1994"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1497.2001.016009606.x"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2012.11.078"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2008.07542.x"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2015.01.046"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0272.2006.00714.x"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1995.tb07422.x"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2012.11268.x"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2006.06401.x"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d7894"}],"container-title":["BJU International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fbju.13413","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bju.13413","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T14:21:45Z","timestamp":1761747705000},"score":1,"resource":{"primary":{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/10.1111\/bju.13413"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2,23]]},"references-count":33,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["10.1111\/bju.13413"],"URL":"https:\/\/doi.org\/10.1111\/bju.13413","archive":["Portico"],"relation":{},"ISSN":["1464-4096","1464-410X"],"issn-type":[{"value":"1464-4096","type":"print"},{"value":"1464-410X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2,23]]},"assertion":[{"value":"2016-02-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}