{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T13:46:52Z","timestamp":1762004812598,"version":"build-2065373602"},"reference-count":26,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,6,2]],"date-time":"2016-06-02T00:00:00Z","timestamp":1464825600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      To describe step\u2010by\u2010step an original urethrovesical anastomosis technique (urethral fixation) in patients undergoing retropubic radical prostatectomy (\n                      <jats:styled-content style=\"fixed-case\">RRP<\/jats:styled-content>\n                      ), to compare their early urinary continence recovery with those in a control group receiving a standard anastomosis technique and to identify the predictors of early urinary continence recovery.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and methods<\/jats:title>\n                    <jats:p>\n                      We compared 70 patients who underwent\n                      <jats:styled-content style=\"fixed-case\">RRP<\/jats:styled-content>\n                      with the urethral\u2010fixation technique with a contemporary control group of 51 patients who received\n                      <jats:styled-content style=\"fixed-case\">RRP<\/jats:styled-content>\n                      with a standard urethrovesical anastomosis. In the urethral\u2010fixation group, the urethrovesical anastomosis was made using eight single sutures. Specifically, to avoid retraction and\/or deviations, we fixed the urethral stump laterally to the medial portion of levator ani muscle. Also, to maintain the normal position in the context of the pelvic floor, we fixed the urethral sphincter deeper to the medial dorsal raphe using a 3\u20100 polydioxanone suture at the 6 o'clock position before completing the incision of the urethral wall. Urinary continence recovery was evaluated at 1, 4, 8 and 12 weeks after catheter removal. Patients self\u2010reporting no urine leak were considered continent. Uni\u2010 and multivariable analyses were used to identify predictors of urinary incontinence at the different follow\u2010up time\u2010points.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The evaluated groups had comparable preoperative variables. At 1 week after catheter removal, 32 (45.7%) patients in the urethral\u2010fixation group and 10 (19.6%) in the control group were continent (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.01). At 4 weeks after catheter removal, 46 (65.7%) patients in the urethral\u2010fixation group and 16 (31.4%) in the control group were continent (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.001). At 8 weeks after catheter removal, 59 (84.3%) patients in the urethral\u2010fixation group and 21 (41.2%) in the control group were continent (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001). Finally, at 12 weeks after catheter removal, 63 (90%) patients in the urethral\u2010fixation group and 32 (62.7%) in the control group were continent (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.001). The urethral\u2010fixation technique was an independent predictor of urinary continence recovery at 1 week [odds ratio (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      ) 4.305;\n                      <jats:italic>P<\/jats:italic>\n                      = 0.002); 4 weeks (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      4.784;\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001); 8 weeks (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      7.678;\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001) and 12 weeks (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      5.152;\n                      <jats:italic>P<\/jats:italic>\n                      = 0.001) after catheter removal.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The urethral\u2010fixation technique significantly improves early urinary continence recovery in comparison with the standard technique. Moreover, our study confirmed that this surgical technique is an independent predictor of urinary continence recovery at 1, 4, 8 and 12 weeks after catheter removal.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.13514","type":"journal-article","created":{"date-parts":[[2016,4,29]],"date-time":"2016-04-29T17:29:07Z","timestamp":1461950947000},"page":"245-253","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Urethral\u2010fixation technique improves early urinary continence recovery in patients who undergo retropubic radical prostatectomy"],"prefix":"10.1111","volume":"119","author":[{"given":"Vincenzo","family":"Ficarra","sequence":"first","affiliation":[{"name":"Urology Unit Department of Experimental and Clinical Medical Sciences University of Udine Udine Italy"},{"name":"Urology Unit Academic Medical Centre Hospital Santa Maria della Misericordia Udine 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