{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T22:51:50Z","timestamp":1775515910325,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,7,10]],"date-time":"2016-07-10T00:00:00Z","timestamp":1468108800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      To construct a nomogram based on preoperative variables to better predict the likelihood of complications occurring within 30 days of radical nephroureterectomy (\n                      <jats:styled-content style=\"fixed-case\">RNU<\/jats:styled-content>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>\n                      The charts of 731 patients undergoing\n                      <jats:styled-content style=\"fixed-case\">RNU<\/jats:styled-content>\n                      at eight academic medical centres between 2002 and 2014 were reviewed. Preoperative clinical, demographic and comorbidity indices were collected. Complications occurring within 30 days of surgery were graded using the modified Clavien\u2013Dindo scale. Multivariate logistic regression determined the association between preoperative variables and post\u2010\n                      <jats:styled-content style=\"fixed-case\">RNU<\/jats:styled-content>\n                      complications. A nomogram was created from the reduced multivariate model with internal validation using the bootstrapping technique with 200 repetitions.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 408 men and 323 women with a median age of 70 years and a body mass index of 27 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      were included. A total of 75% of the cohort was white, 18% had an Eastern Cooperative Oncology Group (\n                      <jats:styled-content style=\"fixed-case\">ECOG<\/jats:styled-content>\n                      ) performance status \u22652, 20% had a Charlson comorbidity index (\n                      <jats:styled-content style=\"fixed-case\">CCI<\/jats:styled-content>\n                      ) score &gt;5 and 50% had baseline chronic kidney disease (\n                      <jats:styled-content style=\"fixed-case\">CKD<\/jats:styled-content>\n                      ) \u2265 stage\n                      <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>\n                      . Overall, 279 patients (38%) experienced a complication, including 61 events (22%) with Clavien grade \u2265\n                      <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>\n                      . A multivariate model identified five variables associated with complications, including patient age, race,\n                      <jats:styled-content style=\"fixed-case\">ECOG<\/jats:styled-content>\n                      performance status,\n                      <jats:styled-content style=\"fixed-case\">CKD<\/jats:styled-content>\n                      stage and\n                      <jats:styled-content style=\"fixed-case\">CCI<\/jats:styled-content>\n                      score. A preoperative nomogram incorporating these risk factors was constructed with an area under curve of 72.2%.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Using standard preoperative variables from this multi\u2010institutional\n                      <jats:styled-content style=\"fixed-case\">RNU<\/jats:styled-content>\n                      experience, we constructed and validated a nomogram for predicting peri\u2010operative complications after\n                      <jats:styled-content style=\"fixed-case\">RNU<\/jats:styled-content>\n                      . Such information may permit more accurate risk stratification on an individual cases basis before major surgery.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.13556","type":"journal-article","created":{"date-parts":[[2016,6,20]],"date-time":"2016-06-20T10:16:43Z","timestamp":1466417803000},"page":"268-275","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":28,"title":["Preoperative nomogram to predict the likelihood of complications after radical nephroureterectomy"],"prefix":"10.1111","volume":"119","author":[{"given":"Jay D.","family":"Raman","sequence":"first","affiliation":[{"name":"Division of Urology Penn State Milton S. Hershey Medical Center Hershey PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu\u2010Kuan","family":"Lin","sequence":"additional","affiliation":[{"name":"Division of Urology Penn State Milton S. Hershey Medical Center Hershey PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahrokh F.","family":"Shariat","sequence":"additional","affiliation":[{"name":"Department of Urology Medical University of Vienna Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura\u2010Maria","family":"Krabbe","sequence":"additional","affiliation":[{"name":"Department of Urology University of Texas Southwestern Medical Center Dallas TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vitaly","family":"Margulis","sequence":"additional","affiliation":[{"name":"Department of Urology University of Texas Southwestern Medical Center Dallas TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alex","family":"Arnouk","sequence":"additional","affiliation":[{"name":"Department of Urology Sidney Kimmel Medical College at Thomas Jefferson University Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Costas D.","family":"Lallas","sequence":"additional","affiliation":[{"name":"Department of Urology Sidney Kimmel Medical College at Thomas Jefferson University Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edouard J.","family":"Trabulsi","sequence":"additional","affiliation":[{"name":"Department of Urology Sidney Kimmel Medical College at Thomas Jefferson University Philadelphia PA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah J.","family":"Drouin","sequence":"additional","affiliation":[{"name":"Department of Urology Pitie Salp\u00e9tri\u00e8re Hospital AP\u2010HP University Paris 6 Paris France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morgan","family":"Roupr\u00eat","sequence":"additional","affiliation":[{"name":"Department of Urology Pitie Salp\u00e9tri\u00e8re Hospital AP\u2010HP University Paris 6 Paris 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