{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T04:50:56Z","timestamp":1780375856262,"version":"3.54.1"},"reference-count":33,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,7,24]],"date-time":"2016-07-24T00:00:00Z","timestamp":1469318400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      To document the long\u2010term outcomes of paediatric augmentation gastrocystoplasty (\n                      <jats:styled-content style=\"fixed-case\">AGC<\/jats:styled-content>\n                      ) in terms of preservation of renal function and maintenance of dryness, and to analyse the rate of complications.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and methods<\/jats:title>\n                    <jats:p>\n                      The medical records of children who had undergone\n                      <jats:styled-content style=\"fixed-case\">AGC<\/jats:styled-content>\n                      between 1992 and 2000 (minimum time interval of 15 years) were reviewed retrospectively. The following data were collected: age at surgery, the cause of bladder dysfunction, functioning of the\n                      <jats:styled-content style=\"fixed-case\">AGC<\/jats:styled-content>\n                      , any complications, and the long\u2010term outcome of the patients. All of the patients were re\u2010contacted by telephone.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 11\n                      <jats:styled-content style=\"fixed-case\">AGC<\/jats:styled-content>\n                      s were carried out between 1992 and 2000, at a median (range) age of 11 (6.5\u201314) years. The diagnosis of patients undergoing\n                      <jats:styled-content style=\"fixed-case\">AGC<\/jats:styled-content>\n                      included myelomeningocele (four), bladder exstrophy (four), posterior urethral valves (one), irradiated bladder (one), and Prune Belly syndrome (one). The median [interquartile range (\n                      <jats:styled-content style=\"fixed-case\">IQR<\/jats:styled-content>\n                      )] follow\u2010up was 17 (15\u201319.5) years. Renal function was preserved or improved in seven of the 11 patients and nine patients were dry after\n                      <jats:styled-content style=\"fixed-case\">AGC<\/jats:styled-content>\n                      . Seven of the 11 patients reported symptoms linked to haematuria\u2010dysuria syndrome, which was resistant to treatment in one case and requiring excision of the gastric patch. Three of the 11 patients developed a tumour on the gastric graft after a median (range) delay of 20 (11\u201322) years after the initial procedure. All had gastric adenocarcinoma of which two were metastatic at the time of diagnosis requiring pelvectomy with pelvic lymph node dissection and adjuvant chemotherapy. Seven of the 11 patients underwent excision of the gastric patch after a median (\n                      <jats:styled-content style=\"fixed-case\">IQR<\/jats:styled-content>\n                      ) time of 11 (8.5\u201320.5) years.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Our long\u2010term data confirmed that most patients undergoing\n                      <jats:styled-content style=\"fixed-case\">AGC<\/jats:styled-content>\n                      had preservation of their renal function and were continent. However, long\u2010term,\n                      <jats:styled-content style=\"fixed-case\">AGC<\/jats:styled-content>\n                      was associated with a significant risk of malignant transformation and a high rate of surgical re\u2010intervention involving removal of the gastric patch. These results question the use of this technique for bladder augmentation, irrespective of the indication. We highlight the importance of strict endoscopic follow\u2010up of all patients already having undergone an\n                      <jats:styled-content style=\"fixed-case\">AGC<\/jats:styled-content>\n                      and the need to inform and educated patients about tumour\u2010related symptoms.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.13558","type":"journal-article","created":{"date-parts":[[2016,6,20]],"date-time":"2016-06-20T10:33:17Z","timestamp":1466418797000},"page":"980-986","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["What is the outcome of paediatric gastrocystoplasty when the patients reach adulthood?"],"prefix":"10.1111","volume":"118","author":[{"given":"Romain","family":"Boissier","sequence":"first","affiliation":[{"name":"Aix\u2010Marseille Universit\u00e9 Marseille France"},{"name":"APHM Service d'Urologie et de Transplantation R\u00e9nale CHU H\u00f4pital la Conception Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugenie","family":"Di Crocco","sequence":"additional","affiliation":[{"name":"Aix\u2010Marseille Universit\u00e9 Marseille France"},{"name":"APHM Service d'Urologie et de Transplantation R\u00e9nale CHU H\u00f4pital la Conception Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice","family":"Faure","sequence":"additional","affiliation":[{"name":"Aix\u2010Marseille Universit\u00e9 Marseille France"},{"name":"APHM Service de Chirurgie P\u00e9diatrique CHU H\u00f4pital Timone Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geraldine","family":"Hery","sequence":"additional","affiliation":[{"name":"Aix\u2010Marseille Universit\u00e9 Marseille France"},{"name":"APHM Service de Chirurgie P\u00e9diatrique CHU H\u00f4pital Timone Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V\u00e9ronique","family":"Delaporte","sequence":"additional","affiliation":[{"name":"Aix\u2010Marseille Universit\u00e9 Marseille France"},{"name":"APHM Service d'Urologie et de Transplantation R\u00e9nale CHU H\u00f4pital la Conception Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Lechevallier","sequence":"additional","affiliation":[{"name":"Aix\u2010Marseille Universit\u00e9 Marseille France"},{"name":"APHM Service d'Urologie et de Transplantation R\u00e9nale CHU H\u00f4pital la Conception Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierre D. 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