{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T16:15:24Z","timestamp":1771258524037,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2017,3,10]],"date-time":"2017-03-10T00:00:00Z","timestamp":1489104000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To study a novel penile reinnervation technique using four sural nerve grafts and end\u2010to\u2010side neurorraphies connecting bilaterally the femoral nerve and the cavernous corpus and the femoral nerve and the dorsal penile nerves.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>\n                      Ten patients (mean [\u00b1\n                      <jats:sc>sd<\/jats:sc>\n                      ; range] age 60.3 [\u00b1 4.8; 54\u201368] years), who had undergone radical prostatectomy (\n                      <jats:styled-content style=\"fixed-case\">RP<\/jats:styled-content>\n                      ) at least 2 years previously, underwent penile reinnervation in the present study. Four patients had undergone radiotherapy after\n                      <jats:styled-content style=\"fixed-case\">RP<\/jats:styled-content>\n                      . All patients reported satisfactory sexual activity prior to\n                      <jats:styled-content style=\"fixed-case\">RP<\/jats:styled-content>\n                      . The surgery involved bridging of the femoral nerve to the dorsal nerve of the penis and the inner part of the corpus cavernosum with sural nerve grafts and end\u2010to\u2010side neurorraphies. Patients were evaluated using the International Index of Erectile Function (\n                      <jats:styled-content style=\"fixed-case\">IIEF<\/jats:styled-content>\n                      ) questionnaire and pharmaco\u2010penile Doppler ultrasonography (\n                      <jats:styled-content style=\"fixed-case\">PPDU<\/jats:styled-content>\n                      ) preoperatively and at 6, 12 and 18 months postoperatively, and using a Clinical Evolution of Erectile Function (\n                      <jats:styled-content style=\"fixed-case\">CEEF<\/jats:styled-content>\n                      ) questionnaire, administered after 36 months.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The\n                      <jats:styled-content style=\"fixed-case\">IIEF<\/jats:styled-content>\n                      scores showed improvements with regard to erectile dysfunction (\n                      <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content>\n                      ), satisfaction with intercourse and general satisfaction. Evaluation of\n                      <jats:styled-content style=\"fixed-case\">PPDU<\/jats:styled-content>\n                      velocities did not reveal any difference between the right and left sides or among the different time points. The introduction of nerve grafts neither caused fibrosis of the corpus cavernosum, nor reduced penile vascular flow.\n                      <jats:styled-content style=\"fixed-case\">CEEF<\/jats:styled-content>\n                      results showed that sexual intercourse began after a mean of 13.7 months with frequency of sexual intercourse varying from once daily to once monthly. Acute complications were minimal. The study was limited by the small number of cases.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      A total of 60% of patients were able to achieve full penetration, on average, 13 months after reinnervation surgery. Patients previously submitted to radiotherapy had slower return of erectile function. We conclude that penile reinnervation surgery is a viable technique, with effective results, and could offer a new treatment method for\n                      <jats:styled-content style=\"fixed-case\">ED<\/jats:styled-content>\n                      after\n                      <jats:styled-content style=\"fixed-case\">RP<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.13772","type":"journal-article","created":{"date-parts":[[2017,1,17]],"date-time":"2017-01-17T02:41:53Z","timestamp":1484620913000},"page":"948-954","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Long\u2010term follow\u2010up of treatment of erectile dysfunction after radical prostatectomy using nerve grafts and end\u2010to\u2010side somatic\u2010autonomic neurorraphy: a new technique"],"prefix":"10.1111","volume":"119","author":[{"given":"Jos\u00e9 Carlos","family":"Souza Trindade","sequence":"first","affiliation":[{"name":"Department of Urology Botucatu School of Medicine State University of S\u00e3o Paulo Sao Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fausto","family":"Viterbo","sequence":"additional","affiliation":[{"name":"Division of Plastic Surgery Botucatu School of Medicine State University of S\u00e3o Paulo Sao Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9","family":"Petean Trindade","sequence":"additional","affiliation":[{"name":"Radiology Botucatu School of Medicine State University of S\u00e3o Paulo Sao Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wagner Jos\u00e9","family":"F\u00e1varo","sequence":"additional","affiliation":[{"name":"Department of Anatomy Faculty of Medical Sciences University of Campinas Campinas Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Carlos Souza","family":"Trindade\u2010Filho","sequence":"additional","affiliation":[{"name":"Department of Urology Botucatu School of Medicine State University of S\u00e3o Paulo Sao Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,3,10]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"351","article-title":"Nerve sparing radical prostatectomy for early stage prostate cancer","volume":"15","author":"Walsh PC","year":"1988","journal-title":"Semin Oncol"},{"key":"e_1_2_7_3_1","first-page":"242","article-title":"Patient\u2010reported urinary continence and sexual function after anatomic radical prostatectomy","volume":"164","author":"Walsh PC","year":"2000","journal-title":"J Urol"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1743-6109.2009.01351.x"},{"key":"e_1_2_7_5_1","doi-asserted-by":"crossref","first-page":"331","DOI":"10.3233\/THC-2011-0635","article-title":"Robot\u2010assisted versus open radical prostatectomy: an evidence\u2010based comparison","volume":"19","author":"Minniti D","year":"2011","journal-title":"Technol Health Care"},{"key":"e_1_2_7_6_1","first-page":"635","article-title":"Comparison of initial results with robotic\u2010assisted laparoscopicradical prostatectomy and open retropubic radical prostatectomy","volume":"104","author":"Otsuki H","year":"2013","journal-title":"Nihon Hinyokika Gakkai Zasshi"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)62093-7"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(01)01403-0"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2006.09.035"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2007.03.043"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-2197.2008.04680.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2008.08.051"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2012.08.089"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1743-6109.2011.02466.x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11934-014-0413-6"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.12033"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-4295(97)00238-0"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0b013e318287a1bc"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2011.07.053"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2015.03.031"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2013.11.049"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2013.08.019"},{"key":"e_1_2_7_23_1","first-page":"561","article-title":"Spontaneous neurotransmitter release in neuromuscular synapsis. 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