{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T23:31:47Z","timestamp":1768001507298,"version":"3.49.0"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,4,2]],"date-time":"2018-04-02T00:00:00Z","timestamp":1522627200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      To compare functional and oncological outcomes of reproductive organ\u2010sparing cystectomy (\n                      <jats:styled-content style=\"fixed-case\">ROSC<\/jats:styled-content>\n                      ) compared with standard cystectomy (\n                      <jats:styled-content style=\"fixed-case\">SC<\/jats:styled-content>\n                      ) in women undergoing orthotopic bladder substitution (\n                      <jats:styled-content style=\"fixed-case\">OBS<\/jats:styled-content>\n                      ).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>\n                      Between 1995 and 2016, 121 consecutive women undergoing\n                      <jats:styled-content style=\"fixed-case\">OBS<\/jats:styled-content>\n                      were prospectively included in this single\u2010centre non\u2010randomized clinical follow\u2010up study comprising an\n                      <jats:styled-content style=\"fixed-case\">ROSC<\/jats:styled-content>\n                      and an\n                      <jats:styled-content style=\"fixed-case\">SC<\/jats:styled-content>\n                      group. Urinary continence, the need for intermittent self\u2010catheterization (\n                      <jats:styled-content style=\"fixed-case\">ISC<\/jats:styled-content>\n                      ), lateral standing micturition cystourethrogram (\n                      <jats:styled-content style=\"fixed-case\">MCUG<\/jats:styled-content>\n                      ), urethral pressure profile findings, if available, and oncological outcomes were assessed and compared between\n                      <jats:styled-content style=\"fixed-case\">ROSC<\/jats:styled-content>\n                      and\n                      <jats:styled-content style=\"fixed-case\">SC<\/jats:styled-content>\n                      .\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      After 12 months, patients who had undergone\n                      <jats:styled-content style=\"fixed-case\">ROSC<\/jats:styled-content>\n                      with\n                      <jats:styled-content style=\"fixed-case\">OBS<\/jats:styled-content>\n                      had significantly higher daytime and nighttime continence rates than patients who had undergone\n                      <jats:styled-content style=\"fixed-case\">SC<\/jats:styled-content>\n                      with\n                      <jats:styled-content style=\"fixed-case\">OBS<\/jats:styled-content>\n                      (87.5% vs 63.5%;\n                      <jats:italic>P<\/jats:italic>\n                      = 0.027 and 87.5% vs 57.7%;\n                      <jats:italic>P<\/jats:italic>\n                      = 0.008), whereas no significant differences were found between groups in\n                      <jats:styled-content style=\"fixed-case\">ISC<\/jats:styled-content>\n                      rates (12.5% vs 12.94%;\n                      <jats:italic>P<\/jats:italic>\n                      &gt; 0.99). The degree of attempted nerve\u2010sparing (none, unilateral, bilateral) positively affected continence rates in both groups. No significant differences were found in local recurrence rates (0% vs 9.4%;\n                      <jats:italic>P<\/jats:italic>\n                      = 0.126), 5\u2010 and 10\u2010year overall survival rates (80.9% and 80.9% vs 64.9% and 55.7%;\n                      <jats:italic>P<\/jats:italic>\n                      = 0.443) or 5\u2010 and 10\u2010year cancer\u2010specific survival rates (84.3% and 84.3% vs 73% and 66.2%;\n                      <jats:italic>P<\/jats:italic>\n                      = 0.431).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      Superior continence rates were found for\n                      <jats:styled-content style=\"fixed-case\">ROSC<\/jats:styled-content>\n                      with an\n                      <jats:styled-content style=\"fixed-case\">OBS<\/jats:styled-content>\n                      compared with\n                      <jats:styled-content style=\"fixed-case\">SC<\/jats:styled-content>\n                      , without a negative impact on oncological outcome.\n                      <jats:styled-content style=\"fixed-case\">ROSC<\/jats:styled-content>\n                      should, therefore, be offered to women receiving an\n                      <jats:styled-content style=\"fixed-case\">OBS<\/jats:styled-content>\n                      whenever justifiable.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.14191","type":"journal-article","created":{"date-parts":[[2018,3,9]],"date-time":"2018-03-09T03:02:35Z","timestamp":1520564555000},"page":"227-235","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Reproductive organ\u2010sparing cystectomy significantly improves continence in women after orthotopic bladder substitution without affecting oncological outcome"],"prefix":"10.1111","volume":"122","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3843-2672","authenticated-orcid":false,"given":"Tobias","family":"Gross","sequence":"first","affiliation":[{"name":"Department of Urology University of Bern Bern Switzerland"},{"name":"Department of Urology Royal Melbourne Hospital Parkville Vic. Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Furrer","sequence":"additional","affiliation":[{"name":"Department of Urology University of Bern Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petra","family":"Schorno","sequence":"additional","affiliation":[{"name":"Department of Urology University of Bern Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3704-6785","authenticated-orcid":false,"given":"Patrick Y.","family":"Wuethrich","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Pain Medicine University of Bern Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc P.","family":"Schneider","sequence":"additional","affiliation":[{"name":"Department of Urology University of Bern Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1908-3286","authenticated-orcid":false,"given":"George N.","family":"Thalmann","sequence":"additional","affiliation":[{"name":"Department of Urology University of Bern Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fiona C.","family":"Burkhard","sequence":"additional","affiliation":[{"name":"Department of Urology University of Bern Bern Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,4,2]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/s001920070030"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.13819"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2011.06.004"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2007.02.048"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-12382-0"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)65082-3"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2009.02.023"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2015.05.015"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(20011001)92:7<1864::AID-CNCR1703>3.0.CO;2-L"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000138249.31644.ec"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(01)68173-4"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-015-1482-y"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(05)64157-2"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOU.0000000000000146"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00192-017-3268-9"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.2000.6010"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2011.12.017"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0094116"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/nau.20431"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2013.02.004"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2009.08.083"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2009.01.020"}],"container-title":["BJU International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fbju.14191","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/bju.14191","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T16:22:26Z","timestamp":1761754946000},"score":1,"resource":{"primary":{"URL":"https:\/\/bjui-journals.onlinelibrary.wiley.com\/doi\/10.1111\/bju.14191"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4,2]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,8]]}},"alternative-id":["10.1111\/bju.14191"],"URL":"https:\/\/doi.org\/10.1111\/bju.14191","archive":["Portico"],"relation":{},"ISSN":["1464-4096","1464-410X"],"issn-type":[{"value":"1464-4096","type":"print"},{"value":"1464-410X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4,2]]},"assertion":[{"value":"2018-04-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}