{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T10:51:36Z","timestamp":1774263096339,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T00:00:00Z","timestamp":1525132800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      To study long\u2010term urinary and sexual function, and cosmetic outcomes in adult patients who underwent single\u2010stage transverse preputial island tube (\n                      <jats:styled-content style=\"fixed-case\">TPIT<\/jats:styled-content>\n                      ) for proximal hypospadias repair in childhood. Long\u2010term data on outcomes of patients with proximal hypospadias with severe coexisting curvature and insufficient urethral plate are scarce, but are necessary to decide which repair technique is most beneficial.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients, Subjects and Methods<\/jats:title>\n                    <jats:p>\n                      Patients with proximal hypospadias operated with\n                      <jats:styled-content style=\"fixed-case\">TPIT<\/jats:styled-content>\n                      (\n                      <jats:styled-content style=\"fixed-case\">TPIT<\/jats:styled-content>\n                      Group) were compared to patients with distal hypospadias repair (Distal Group) and to a control group of male medical students (Control Group). Participants completed the International Prostate Symptom Score, the International Index of Erectile Function (\n                      <jats:styled-content style=\"fixed-case\">IIEF<\/jats:styled-content>\n                      \u201015), additional non\u2010validated questions, and performed uroflowmetry. Cosmesis was assessed in the patients with hypospadias using the Pediatric Penile Perception Score (\n                      <jats:styled-content style=\"fixed-case\">PPPS<\/jats:styled-content>\n                      ); stretched penile length was also measured.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of the 121 eligible patients with hypospadias, 54 with either\n                      <jats:styled-content style=\"fixed-case\">TPIT<\/jats:styled-content>\n                      or distal hypospadias repairs participated. The\n                      <jats:styled-content style=\"fixed-case\">TPIT<\/jats:styled-content>\n                      Group comprised 12 patients (median age of 20.0\u00a0years) and the Distal Group comprised 42 patients (median age of 19.6\u00a0years). The complication rates were similar, at 8 of the 12 patients in the\n                      <jats:styled-content style=\"fixed-case\">TPIT<\/jats:styled-content>\n                      Group vs 26\/42 (62%) in the Distal Group (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.76). Urinary outcomes were similar in the\n                      <jats:styled-content style=\"fixed-case\">TPIT<\/jats:styled-content>\n                      , Distal, and the Control (comprised of 148 medical students with a median age of 21.0\u00a0years) groups. The\n                      <jats:styled-content style=\"fixed-case\">TPIT<\/jats:styled-content>\n                      Group had a lower maximum urinary flow rate compared to the Control Group, at 24.1 vs 28.6\u00a0mL\/s (\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.05).\n                      <jats:styled-content style=\"fixed-case\">IIEF<\/jats:styled-content>\n                      \u201015 scores were similar in the\n                      <jats:styled-content style=\"fixed-case\">TPIT<\/jats:styled-content>\n                      , Distal and Control groups, except for \u2018Orgasmic Function\u2019 (7.5 vs 10.0 vs 10.0, respectively;\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.01). Although the\n                      <jats:styled-content style=\"fixed-case\">TPIT<\/jats:styled-content>\n                      Group had a smaller penile length compared to the Distal Group (10.1 vs 12.9 cm,\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.01),\n                      <jats:styled-content style=\"fixed-case\">PPPS<\/jats:styled-content>\n                      outcomes were similar.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      In these\n                      <jats:styled-content style=\"fixed-case\">TPIT<\/jats:styled-content>\n                      patients, long\u2010term urinary, sexual and cosmetic outcomes were similar to those in patients with distal hypospadias repairs and controls.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.14234","type":"journal-article","created":{"date-parts":[[2018,4,6]],"date-time":"2018-04-06T18:30:05Z","timestamp":1523039405000},"page":"463-471","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Proximal hypospadias treated with a transverse preputial island tube: long\u2010term functional, sexual, and cosmetic outcomes"],"prefix":"10.1111","volume":"122","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8155-0885","authenticated-orcid":false,"given":"Sybren P.","family":"Rynja","sequence":"first","affiliation":[{"name":"University Medical Center (UMC) Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom P.V.M.","family":"de Jong","sequence":"additional","affiliation":[{"name":"University Children's Hospital UMC Utrecht Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.L.H. 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