{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T02:43:44Z","timestamp":1773283424297,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2019,7,12]],"date-time":"2019-07-12T00:00:00Z","timestamp":1562889600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>\n                      To evaluate the technical feasibility, oncological and functional outcomes of nerve sparing cystoprostatectomy (\n                      <jats:styled-content style=\"fixed-case\">NSCP<\/jats:styled-content>\n                      ) and prostate capsule\u2010sparing cystectomy (\n                      <jats:styled-content style=\"fixed-case\">PCSC<\/jats:styled-content>\n                      ) for the treatment of organ\u2010confined bladder cancer at a single referral centre.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>\n                      From April 2001 to June 2012, 60 patients underwent\n                      <jats:styled-content style=\"fixed-case\">PCSC<\/jats:styled-content>\n                      and 47 were treated with\n                      <jats:styled-content style=\"fixed-case\">NSCP<\/jats:styled-content>\n                      . Inclusion criteria for\n                      <jats:styled-content style=\"fixed-case\">PCSC<\/jats:styled-content>\n                      were: fully informed consent for the well\u2010motivated patient; negative transurethral resection of the bladder neck; normal prostatic specific antigen (PSA) level (defined as &lt;4\u00a0ng\/\n                      <jats:styled-content style=\"fixed-case\">dL<\/jats:styled-content>\n                      during the first year of the study, which was later lowered to 2.5\u00a0ng\/\n                      <jats:styled-content style=\"fixed-case\">dL<\/jats:styled-content>\n                      ); and normal transrectal ultrasonography, with biopsy for any suspicious nodule. Patients received a complete oncological and functional follow\u2010up. The Kaplan\u2013Meier method was used to depict survival outcomes after surgery.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      After a median follow\u2010up of 73 and 62\u00a0months for\n                      <jats:styled-content style=\"fixed-case\">PCSC<\/jats:styled-content>\n                      and\n                      <jats:styled-content style=\"fixed-case\">NSCP<\/jats:styled-content>\n                      , respectively, the 5\u2010year cancer\u2010specific survival was 90% for the\n                      <jats:styled-content style=\"fixed-case\">PCSC<\/jats:styled-content>\n                      group and 78% for the\n                      <jats:styled-content style=\"fixed-case\">NSCP<\/jats:styled-content>\n                      group (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.055). Considering complications within 30\u00a0days after surgery, 13% and 21% patients had Clavien\n                      <jats:styled-content style=\"fixed-case\">\u2265III<\/jats:styled-content>\n                      complications in the PCSC and\n                      <jats:styled-content style=\"fixed-case\">NSCP<\/jats:styled-content>\n                      groups, respectively (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.2). For functional outcomes, at 3\u00a0months after surgery, 54 (90%) and 24 (51%) patients reported full recovery of daytime urinary continence in the\n                      <jats:styled-content style=\"fixed-case\">PCSC<\/jats:styled-content>\n                      and\n                      <jats:styled-content style=\"fixed-case\">NSCP<\/jats:styled-content>\n                      groups, respectively (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.001); and for erectile function recovery, 32 (53%) and four (9%) patients in the\n                      <jats:styled-content style=\"fixed-case\">PCSC<\/jats:styled-content>\n                      group and in the\n                      <jats:styled-content style=\"fixed-case\">NSCP<\/jats:styled-content>\n                      group were respectively potent without any treatment (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      NSCP and\n                      <jats:styled-content style=\"fixed-case\">PCSC<\/jats:styled-content>\n                      are appropriate for a subset of patients with bladder cancer, with excellent oncological and functional results. These surgical procedures should be proposed to well\u2010motivated patients.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.14850","type":"journal-article","created":{"date-parts":[[2019,6,20]],"date-time":"2019-06-20T15:51:14Z","timestamp":1561045874000},"page":"253-259","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Long\u2010term functional and oncological outcomes of nerve\u2010sparing and prostate capsule\u2010sparing cystectomy: a single\u2010centre experience"],"prefix":"10.1111","volume":"125","author":[{"given":"Mohamed","family":"Saad","sequence":"first","affiliation":[{"name":"Department of Urology Institut Mutualiste Montsouris Universit\u00e9 Paris Descartes Paris France"},{"name":"Cancer Center Southend University Hospital Southend\u2010on\u2010sea 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