{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T22:46:44Z","timestamp":1788216404598,"version":"build-2803163510"},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,8,26]],"date-time":"2019-08-26T00:00:00Z","timestamp":1566777600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"St Joseph's Hospital Foundation"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      To compare the healthcare utilisation and repeat surgical treatment rate amongst older men undergoing an electrosurgical\u2010\n                      <jats:styled-content style=\"fixed-case\">transurethral resection of the prostate (TURP)<\/jats:styled-content>\n                      vs photoselective vaporisation of the prostate (\n                      <jats:styled-content style=\"fixed-case\">PVP<\/jats:styled-content>\n                      ), as the real\u2010world implementation and outcomes of laser\u2010based\n                      <jats:styled-content style=\"fixed-case\">treatment<\/jats:styled-content>\n                      have not been well studied.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>\n                      We used administrative data from the province of Ontario, Canada, to identify all men aged &gt;66\u00a0years who underwent their first electrosurgical\u2010\n                      <jats:styled-content style=\"fixed-case\">TURP<\/jats:styled-content>\n                      \/\n                      <jats:styled-content style=\"fixed-case\">PVP<\/jats:styled-content>\n                      between 2003 and 2016. Our primary exposure was type of procedure (\n                      <jats:styled-content style=\"fixed-case\">PVP<\/jats:styled-content>\n                      or electrosurgical\u2010\n                      <jats:styled-content style=\"fixed-case\">TURP<\/jats:styled-content>\n                      ). Our primary outcome was need for repeat surgical treatment. The primary analysis was an adjusted marginal Cox model approach, which accounted for clustering of patients within\u00a0surgeons; adjusted hazard ratios (\n                      <jats:styled-content style=\"fixed-case\">aHRs<\/jats:styled-content>\n                      ) or odds ratios (\n                      <jats:styled-content style=\"fixed-case\">aORs<\/jats:styled-content>\n                      ) and 95% confidence intervals (CIs) are reported.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We identified 52\u00a0748 men: 6838 (13%) underwent\n                      <jats:styled-content style=\"fixed-case\">PVP<\/jats:styled-content>\n                      , and 45\u00a0910 (87%) underwent electrosurgical\u2010\n                      <jats:styled-content style=\"fixed-case\">TURP<\/jats:styled-content>\n                      . The median age was similar, and\n                      <jats:styled-content style=\"fixed-case\">PVP<\/jats:styled-content>\n                      became more common with time. Compared to the\n                      <jats:styled-content style=\"fixed-case\">PVP<\/jats:styled-content>\n                      group, more patients in the electrosurgical\u2010TURP group had prior gross haematuria or urinary retention, and fewer had used anticoagulants, \u03b1\u2010blockers, or 5\u03b1\u2010reductase inhibitors. The need for repeat surgical treatment was significantly higher amongst men who had\n                      <jats:styled-content style=\"fixed-case\">PVP<\/jats:styled-content>\n                      (\n                      <jats:styled-content style=\"fixed-case\">aHR<\/jats:styled-content>\n                      1.57,\n                      <jats:styled-content style=\"fixed-case\">95% CI<\/jats:styled-content>\n                      1.38\u20131.78; absolute risk difference +2.3%).\n                      <jats:styled-content style=\"fixed-case\">PVP<\/jats:styled-content>\n                      was also associated with a slightly higher risk of return to the emergency room within 30\u00a0days (\n                      <jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>\n                      1.11,\n                      <jats:styled-content style=\"fixed-case\">95% CI<\/jats:styled-content>\n                      1.01\u20131.22) and a significantly lower risk of blood transfusion (\n                      <jats:styled-content style=\"fixed-case\">aOR<\/jats:styled-content>\n                      0.24,\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      0.16\u20130.37); the majority of\n                      <jats:styled-content style=\"fixed-case\">PVP<\/jats:styled-content>\n                      cases were done with a &lt;24\u00a0h stay (73%) vs electrosurgical\u2010\n                      <jats:styled-content style=\"fixed-case\">TURP<\/jats:styled-content>\n                      (7%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      While some of the expected benefits of\n                      <jats:styled-content style=\"fixed-case\">PVP<\/jats:styled-content>\n                      (such as reduced transfusion risk and shorter length of stay) were observed, the significantly higher rate of repeat surgical treatment compared to electrosurgical\u2010\n                      <jats:styled-content style=\"fixed-case\">TURP<\/jats:styled-content>\n                      may represent an important difference in implementation of this technology outside of clinical trials.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.14891","type":"journal-article","created":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T04:03:55Z","timestamp":1565150635000},"page":"1047-1054","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Population\u2010based assessment of re\u2010treatment and healthcare utilisation after photoselective vaporisation of the prostate or electrosurgical transurethral resection of the prostate"],"prefix":"10.1111","volume":"124","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7093-558X","authenticated-orcid":false,"given":"Blayne","family":"Welk","sequence":"first","affiliation":[{"name":"Department of Surgery Western University London ON Canada"},{"name":"Department of Epidemiology and Biostatistics Western University London ON Canada"},{"name":"Institute for Clinical Evaluative Sciences London ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Reid","sequence":"additional","affiliation":[{"name":"Institute for Clinical Evaluative Sciences London ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9319-1747","authenticated-orcid":false,"given":"Michael","family":"Ordon","sequence":"additional","affiliation":[{"name":"Institute for Clinical Evaluative Sciences London ON Canada"},{"name":"Department of Surgery University of Toronto London ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassan","family":"Razvi","sequence":"additional","affiliation":[{"name":"Department of Surgery Western University London ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Campbell","sequence":"additional","affiliation":[{"name":"Department of Surgery Western University London ON Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,8,26]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2018.05.048"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2006.06397.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199501123320202"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11934-016-0603-5"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2014.06.017"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10103-015-1843-1"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2012.04.051"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2015.07.054"},{"key":"e_1_2_8_10_1","first-page":"392","article-title":"Interventions in randomised controlled trials in surgery: issues to consider during trial design trials","volume":"16","author":"Blencowe NS","year":"2015","journal-title":"BioMed Central"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euf.2017.09.011"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001885"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(96)00018-6"},{"key":"e_1_2_8_14_1","first-page":"67","article-title":"Coding accuracy of administrative drug claims in the Ontario Drug Benefit database","volume":"10","author":"Levy AR","year":"2003","journal-title":"Can J Clin Pharmacol"},{"key":"e_1_2_8_15_1","first-page":"339","volume-title":"Patterns of Health Care in Ontario. 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