{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T04:23:40Z","timestamp":1789705420656,"version":"4.0.1"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,10,6]],"date-time":"2019-10-06T00:00:00Z","timestamp":1570320000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004470","name":"Daewoong Pharmaceutical Company","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004470","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>\n                      To evaluate the effectiveness of poloxamer\u2010based thermo\u2010sensitive sol\u2013gel instillation, after transurethral resection of the prostate (\n                      <jats:styled-content style=\"fixed-case\">TURP<\/jats:styled-content>\n                      ), for preventing urethral stricture.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>\n                      In all, 198 patients underwent\n                      <jats:styled-content style=\"fixed-case\">TURP<\/jats:styled-content>\n                      for benign prostatic hyperplasia. Recruited patients were randomly divided into two groups: groups A and B. Patients in Group A (100 patients, experimental group) received poloxamer\u2010based thermo\u2010sensitive sol\u2013gel instillation and patients in the Group B (98 patients, control group) received lubricant instillation after\n                      <jats:styled-content style=\"fixed-case\">TURP<\/jats:styled-content>\n                      . Each patient was evaluated at 4 (V1), 12 (V2), and 24\u00a0weeks (V3) after TURP. The effectiveness of poloxamer\u2010based thermo\u2010sensitive sol\u2013gel instillation was evaluated based on the International Prostate Symptom Score (\n                      <jats:styled-content style=\"fixed-case\">IPSS<\/jats:styled-content>\n                      ), IPSS\u2010Quality of Life (QoL), Overactive bladder questionnaire (\n                      <jats:styled-content style=\"fixed-case\">OAB<\/jats:styled-content>\n                      \u2010q), maximum urinary flow rate (Q\n                      <jats:sub>max<\/jats:sub>\n                      ), post\u2010void residual urine volume (\n                      <jats:styled-content style=\"fixed-case\">PVR<\/jats:styled-content>\n                      ), and cystoscopy.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Amongst the initial 198 participants, 80 patients in Group A and 83 in Group B completed the study. There were no significant differences in\n                      <jats:styled-content style=\"fixed-case\">IPSS<\/jats:styled-content>\n                      \u2010QoL and\n                      <jats:styled-content style=\"fixed-case\">OAB<\/jats:styled-content>\n                      \u2010q between the groups. However, Q\n                      <jats:sub>max<\/jats:sub>\n                      was significantly different between groups A and B, at a mean (SD) of 18.92\u00a0(9.98) vs 15.58\u00a0(9.24)\u00a0\n                      <jats:styled-content style=\"fixed-case\">mL<\/jats:styled-content>\n                      \/s (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.028) at 24\u00a0weeks after TURP. On cystoscopic examination, urethral stricture after\n                      <jats:styled-content style=\"fixed-case\">TURP<\/jats:styled-content>\n                      was found in two of the 80 patients in Group A and 10 of 83 in Group B (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.023).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>\n                      Poloxamer\u2010based thermo\u2010sensitive sol\u2013gel instillation after\n                      <jats:styled-content style=\"fixed-case\">TURP<\/jats:styled-content>\n                      lowered the incidence of urethral stricture.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.14902","type":"journal-article","created":{"date-parts":[[2019,8,24]],"date-time":"2019-08-24T08:36:16Z","timestamp":1566635776000},"page":"160-167","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Effects of poloxamer\u2010based thermo\u2010sensitive sol\u2013gel agent on urethral stricture after transurethral resection of the prostate for benign prostatic hyperplasia: a multicentre, single\u2010blinded, randomised controlled trial"],"prefix":"10.1111","volume":"125","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9729-3457","authenticated-orcid":false,"given":"Jae Hoon","family":"Chung","sequence":"first","affiliation":[{"name":"Department of Urology Samsung Medical Center Sungkyunkwan University School of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8755-0774","authenticated-orcid":false,"given":"Kyu Shik","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Urology Hanyang University College of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Duck","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Urology Eulji Medical Center Eulji University School of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae Hyo","family":"Kim","sequence":"additional","affiliation":[{"name":"Departments of Urology College of Medicine Dong\u2010A University College of Medicine Busan South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ki Soo","family":"Lee","sequence":"additional","affiliation":[{"name":"Departments of Urology College of Medicine Dong\u2010A University College of Medicine Busan South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheol Young","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Urology Hallym University College of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joon Hwa","family":"Noh","sequence":"additional","affiliation":[{"name":"Department of Urology Kwangju Christian Hospital Gwangju South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun Seok","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Urology Kwangju Christian Hospital Gwangju South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Won Tae","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Urology College of Medicine Chungbuk National University Cheongju South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung Hwan","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Urology Yonsei University College of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4490-3610","authenticated-orcid":false,"given":"Jae Heon","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Urology Soonchunhyang University College of Medicine Seoul South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae Nam","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Urology Pusan National University Hospital Busan South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wan","family":"Huh","sequence":"additional","affiliation":[{"name":"Daewoong Pharmaceutical Co. 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