{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T11:38:43Z","timestamp":1788349123813,"version":"build-2803163510"},"reference-count":36,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2020,6,16]],"date-time":"2020-06-16T00:00:00Z","timestamp":1592265600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To provide a clinical framework and key guideline statements to assist clinicians in the evidence\u2010based management of Peyronie\u2019s disease (PD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a review of the published literature relevant to PD management, with an emphasis on published clinical guidelines. References used in the text have been assessed according to their level of evidence, and guideline recommendations have been graded based on the Oxford Centre for Evidence\u2010based Medicine Levels of Evidence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The management of PD involves taking a detailed penile and sexual history, with a focused penile examination to identify plaque and hourglass deformity, and digital photographs of the erect curved (deformed) penis. Penile colour Duplex ultrasonography evaluates tunical plaque and underlying cavernosal smooth muscle and blood flow variables. The current therapy for PD can be divided into two main groups, namely, medical therapy and penile reconstructive surgery, and the patient should be counselled on the benefits and risks of each treatment option.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Peyronie\u2019s disease remains a clinical challenge and presents a considerable therapeutic dilemma as the current therapy addresses existing penile curvature only and is not very effective in preventing future penile fibrosis and\/or reversing underlying erectile dysfunction.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.15057","type":"journal-article","created":{"date-parts":[[2020,6,16]],"date-time":"2020-06-16T07:13:17Z","timestamp":1592291597000},"page":"12-17","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":36,"title":["A clinical pathway for the management of Peyronie\u2019s disease: integrating clinical guidelines from the International Society of Sexual Medicine, American Urological Association and European Urological Association"],"prefix":"10.1111","volume":"126","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3373-3668","authenticated-orcid":false,"given":"Eric","family":"Chung","sequence":"first","affiliation":[{"name":"Department of Urology Princess Alexandra Hospital University of Queensland Brisbane Qld Australia"},{"name":"Andro Urology Centre Brisbane Qld Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Gillman","sequence":"additional","affiliation":[{"name":"St Andrew\u2019s War Memorial Hospital Brisbane Qld Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Tuckey","sequence":"additional","affiliation":[{"name":"Brightside Hospital Auckland New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shane","family":"La Bianca","sequence":"additional","affiliation":[{"name":"Perth Urology Clinic Perth WA Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Love","sequence":"additional","affiliation":[{"name":"Urology South Moorabbin Vic. 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