{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T22:46:44Z","timestamp":1788216404340,"version":"build-2803163510"},"reference-count":28,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2020,9,30]],"date-time":"2020-09-30T00:00:00Z","timestamp":1601424000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare transurethral resection in saline (TURIS), Greenlight laser vapo\u2010enucleation of the prostate (GL.PVEP), and holmium laser enucleation of the prostate (HoLEP), for controlling lower urinary tract symptoms secondary to large benign prostatic hyperplasia (BPH) and to assess non\u2010inferiority of 3\u2010year re\u2010treatment rates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>Eligible patients with BPH (prostate size 80\u2013150\u00a0mL) were randomly assigned to one of the intervention groups. Non\u2010inferiority of re\u2010treatment rate was evaluated using a one\u2010sided test at 5% level of significance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      At the time of analysis, 60 GL.PVEP, 60 HoLEP and 62 TURIS procedures were included. Perioperative parameters were comparable between groups; however, the operative time was longer in GL.PVEP vs HoLEP and TURIS, at a mean (SD) of 92\u00a0(32) vs 73\u00a0(30) and 83\u00a0(28)\u00a0min (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.005); and was less effective with a mean (SD) removal of 1.2\u00a0(0.4) vs 1.7\u00a0(0.7) and 1.4\u00a0(0.6)\u00a0g\/min (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.001), respectively. Perioperative complications and need for auxiliary procedures were similar in the three groups; however, there was a significantly higher rate of capsular perforation in TURIS group (five, 8%) compared to one (1.6%) in the GL.PVEP group and none in the HoLEP group (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.01). There was a significantly longer hospital stay, catheter\u2010time and higher rate of blood transfusion in the TURIS group. There was significant but comparable improvements in the International Prostate Symptom Score in three groups at different follow\u2010up points. At 3\u00a0years, re\u2010treatment for recurrent bladder outlet obstruction was required more after GL.PVEP and TURIS. More re\u2010do surgeries for recurrent obstructing prostate adenoma was reported after GL.PVEP (four, 6.7%) and TURIS (six, 9.7%) than for HoLEP (none) (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.04).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The perioperative outcomes of GL.PVEP and HoLEP surpassed that of TURIS for the treatment of large prostates, but with a significantly prolonged operative time with GL.PVEP. The three techniques achieve good functional outcomes; however, 3\u2010year re\u2010treatment rates following TURIS and GL.PVEP were inferior to HoLEP.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.15161","type":"journal-article","created":{"date-parts":[[2020,7,6]],"date-time":"2020-07-06T22:10:55Z","timestamp":1594073455000},"page":"731-738","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":51,"title":["Randomised trial of bipolar resection vs holmium laser enucleation vs Greenlight laser vapo\u2010enucleation of the prostate for treatment of large benign prostate obstruction: 3\u2010years outcomes"],"prefix":"10.1111","volume":"126","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0938-0161","authenticated-orcid":false,"given":"Ahmed M.","family":"Elshal","sequence":"first","affiliation":[{"name":"Mansoura Urology and Nephrology Center Mansoura Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Soltan","sequence":"additional","affiliation":[{"name":"Mansoura Urology and Nephrology Center Mansoura Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nasr A.","family":"El\u2010Tabey","sequence":"additional","affiliation":[{"name":"Mansoura Urology and Nephrology Center Mansoura Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud","family":"Laymon","sequence":"additional","affiliation":[{"name":"Mansoura Urology and Nephrology Center Mansoura Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adel","family":"Nabeeh","sequence":"additional","affiliation":[{"name":"Mansoura Urology and Nephrology Center Mansoura Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,9,30]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2008.03.058"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-410X.2003.04474.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2014.06.017"},{"key":"e_1_2_7_5_1","volume-title":"American Urological Association Guideline: Management of Benign Prostatic Hyperplasia","author":"McVary KT","year":"2010"},{"key":"e_1_2_7_6_1","article-title":"Guidelines on the management of non\u2010neurogenic male lower urinary tract symptoms (LUTS), incl. 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