{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T09:31:19Z","timestamp":1769247079315,"version":"3.49.0"},"reference-count":25,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,12,11]],"date-time":"2020-12-11T00:00:00Z","timestamp":1607644800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To compare the occurrence of emptying dysfunction between surgical techniques for orthotopic neobladder suspended with round ligament (rONB) and the standard procedure (sONB).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>A prospective randomised controlled trial was performed in a single centre of female patients undergoing creation of an ONB using rONB or sONB. Patients were followed for \u226524\u00a0months after ONB. The primary endpoints were significant post\u2010void residual urine volume (sPVR) and need for clean intermittent catheterisation (CIC) at 24\u00a0months postoperatively. The secondary endpoints included early and late complications, urodynamic profile, and ONB continence.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Between January 2011 and October 2017, the trial enrolled 85 patients, of whom 82 were randomised. A total of 41 patients had a rONB and 41 a sONB. At 24\u00a0months, 17 of the 37 patients with a sONB and nine of the 39 patients with a rONB had a sPVR. The cumulative risk of a sPVR was significantly lower in the rONB group (23.1%) vs the sONB group (45.9%) (hazard ratio [HR] 0.43, 95% confidence interval [CI], 0.19\u20130.96;\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.040). In all, 15 of the 37 patients with a sONB and four of the 39 patients with a rONB needed CIC. The cumulative risk of requiring CIC was significantly lower in the rONB group (10.3%) vs the sONB group (40.5%) (HR 0.22, 95% CI 0.07\u20130.67;\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.008) at 24\u00a0months. Multivariable Cox regression analysis also showed that the rONB type was an independently protective factor for sPVR and CIC. The rates of early (0\u201390\u00a0days) and late complication (&gt;90\u00a0days) were 54.1% and 13.5% in the sONB group, and 64.1% and 10.3% in the rONB group, respectively. There were no significant differences in complications, urodynamic profile or ONB continence. A major limitation is the small sample size at a single centre.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Posterior support with round ligament for an ONB significantly improved the emptying of the ONB and resulted in a reduced need for CIC. The surgical modification is a feasible and safe technique without additional complication\u2010related surgeries.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.15306","type":"journal-article","created":{"date-parts":[[2020,12,4]],"date-time":"2020-12-04T11:45:21Z","timestamp":1607082321000},"page":"187-195","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Round ligament suspending treatment in orthotopic ileal\u2010neobladder after radical cystectomy in women: a single\u2010centre prospective randomised trial"],"prefix":"10.1111","volume":"128","author":[{"given":"Xiaozhou","family":"Zhou","sequence":"first","affiliation":[{"name":"Department of Urology Urology Institute of PLA Southwest Hospital Third Military Medical University (Army Medical University) Chongqing 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