{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T15:24:16Z","timestamp":1784042656469,"version":"3.55.0"},"reference-count":27,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,6,13]],"date-time":"2021-06-13T00:00:00Z","timestamp":1623542400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To compare the oncological outcomes of patients with upper tract urothelial carcinoma (UTUC) undergoing kidney\u2010sparing surgery (KSS) with fibre\u2010optic (FO) vs digital (D) ureteroscopy (URS). To evaluate the oncological impact of image\u2010enhancement technologies such as narrow\u2010band imaging (NBI) and Image1\u2010S in patients with UTUC.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>The Clinical Research Office of the Endourology Society (CROES)\u2010UTUC registry is an international, multicentre, cohort study prospectively collecting data on patients with UTUC. Patients undergoing flexible FO\u2010 or D\u2010URS for diagnostic or diagnostic and treatment purposes were included. Differences between groups in terms of overall survival (OS) and disease\u2010free survival (DFS) were evaluated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The CROES registry included 2380 patients from 101 centres and 37 countries, of whom 401 patients underwent URS (FO\u2010URS 186 and D\u2010URS 215). FO\u2010URS were performed more frequently for diagnostic purposes, while D\u2010URS was peformed when a combined diagnostic and treatment strategy was planned. Intra\u2010 and postoperative complications did not differ between the groups. The 5\u2010year OS and DFS rates were 91.5% and 66.4%, respectively. The mean OS was 42\u00a0months for patients receiving FO\u2010URS and 39\u00a0months for those undergoing D\u2010URS (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.9); the mean DFS was 28\u00a0months in the FO\u2010URS group and 21\u00a0months in the D\u2010URS group (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.001). In patients who received URS with treatment purposes, there were no differences in OS (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.9) and DFS (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.7). NBI and Image1\u2010S technologies did not improve OS or DFS over D\u2010URS.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>D\u2010URS did not provide any oncological advantage over FO\u2010URS. Similarly, no differences in terms of OS and DFS were found when image\u2010enhancement technologies were compared to D\u2010URS. These findings underline the importance of surgeon skills and experience, and reinforce the need for the centralisation of UTUC care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.15494","type":"journal-article","created":{"date-parts":[[2021,5,24]],"date-time":"2021-05-24T07:35:12Z","timestamp":1621841712000},"page":"734-743","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Flexible fibre optic vs digital ureteroscopy and enhanced vs unenhanced imaging for diagnosis and treatment of upper tract urothelial carcinoma (UTUC): results from the Clinical Research Office of the Endourology Society (CROES)\u2010UTUC registry"],"prefix":"10.1111","volume":"128","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8443-8453","authenticated-orcid":false,"given":"Francesco","family":"Soria","sequence":"first","affiliation":[{"name":"Division of Urology Department of Surgical Sciences San Giovanni Battista Hospital University of Studies of Torino Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Pilar","family":"Laguna","sequence":"additional","affiliation":[{"name":"Department of Urology Medipol Mega University Hospital Istanbul Medipol University Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morgan","family":"Roupret","sequence":"additional","affiliation":[{"name":"GRC 5 Predictive ONCO\u2010URO AP\u2010HP Urology Pitie\u2010Salpetriere Hospital Sorbonne University Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricio","family":"Garcia\u2010Marchinena","sequence":"additional","affiliation":[{"name":"Department of Urology Hospital Italiano de Buenos Aires Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariano Sebasti\u00e1n","family":"Gonzalez","sequence":"additional","affiliation":[{"name":"Department of Urology Hospital Italiano de Buenos Aires Buenos Aires 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