{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T14:23:12Z","timestamp":1767968592867,"version":"3.49.0"},"reference-count":27,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,12,9]],"date-time":"2021-12-09T00:00:00Z","timestamp":1639008000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To elucidate the national burden of emergency department (ED) visits for radiation cystitis (RC), a known complication of radiation therapy (RT) to the pelvic area, among patients with a prostate cancer history, and identify those who are at increased risk of requiring invasive measures.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and methods<\/jats:title>\n                    <jats:p>This study queried the Nationwide Emergency Department Sample for all ED visits from January 2006 to December 2015 with a primary diagnosis of RC and secondary diagnosis of prostate cancer. ED visits were characterised by demographic factors, socioeconomic factors, and hospital characteristics. Weighted frequencies were used to create national estimates for all data analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A weighted total of 17\u2009382 ED visits occurred for RC among patients with a prostate cancer history, of which 9655 (55.5%) were treated with an invasive procedure. Notable factors associated with undergoing an invasive procedure included having a prior prostatectomy (odds ratio [OR] 5.48, 95% confidence interval [CI] 2.62\u201311.46), urinary retention (OR 1.35, 95% CI 1.12\u20131.64), haematuria (OR 1.20, 95% CI 1.01\u20131.42), and undergoing a blood transfusion (OR 2.12, 95% CI 1.72\u20132.62). ED visits that were associated with invasive procedures had a higher median total charge ($34\u2009707.53 vs $15\u2009632.53) and an increased median length of stay (5 vs 3\u2009days) compared to visits without an invasive procedure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Among ED visits for RC in prostate cancer, approximately one half required an invasive procedure for treatment. While RT remains an effective modality for patients with prostate cancer, providers should be mindful of RC as a potential complication.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.15650","type":"journal-article","created":{"date-parts":[[2021,11,22]],"date-time":"2021-11-22T06:49:01Z","timestamp":1637563741000},"page":"208-216","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Emergency department visits for radiation cystitis among patients with a prostate cancer history"],"prefix":"10.1111","volume":"130","author":[{"given":"Victor","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Therapeutic Radiology Yale School of Medicine  New Haven CT USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi","family":"An","sequence":"additional","affiliation":[{"name":"Department of Therapeutic Radiology Yale School of Medicine  New Haven CT USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henry S.","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Therapeutic Radiology Yale School of Medicine  New Haven CT USA"},{"name":"Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center Yale School of Medicine  New Haven CT USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James B.","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Therapeutic Radiology Yale School of Medicine  New Haven CT USA"},{"name":"Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center Yale School of Medicine  New Haven CT USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon P.","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Urology University of Colorado Anschutz Medical Center  Aurora CO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6602-7204","authenticated-orcid":false,"given":"Vikram","family":"Jairam","sequence":"additional","affiliation":[{"name":"Department of Therapeutic Radiology Yale School of Medicine  New Haven CT USA"},{"name":"Cancer Outcomes, Public Policy, and Effectiveness Research (COPPER) Center Yale School of Medicine  New Haven CT USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,12,9]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1606220"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmp.2016.02.012"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.3747\/co.v17i0.704"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1006\/gyno.1994.1278"},{"key":"e_1_2_9_6_1","first-page":"CD001773","article-title":"Non\u2010surgical interventions for late radiation cystitis in patients who have received radical radiotherapy to the pelvis","volume":"3","author":"Denton AS","year":"2002","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urpr.2015.10.007"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(94)00431-J"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2009.06.034"},{"key":"e_1_2_9_10_1","first-page":"224","article-title":"Evaluation of the impact of the urinary symptoms on quality of life of patients with painful bladder syndrome\/chronic pelvic pain and radiation cystitis: EURCIS study","volume":"38","author":"Rapariz\u2010Gonz\u00e1lez M","year":"2014","journal-title":"Actas Urol Esp"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2019.05.034"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000049760"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2014.06.030"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.14516"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.1655"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.14145"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2018.36.30_suppl.230"},{"key":"e_1_2_9_18_1","unstructured":"U.S. Bureau of Labor Statistics.Medical care price history from 1947 through 2020. 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