{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T09:47:54Z","timestamp":1792144074906,"version":"4.4.0"},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,3,5]],"date-time":"2022-03-05T00:00:00Z","timestamp":1646438400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2022,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To assess the accuracy of dynamic sentinel lymph node biopsy (DSNB) after negative ultrasonography (US) guided fine\u2010needle aspiration (FNA) for inguinal lymph node (ILN) staging.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>We performed a retrospective analysis of men with \u2265T1G2 penile cancer and negative inguinal US\u2010guided FNA undergoing DSNB. Men with suspicious US but negative FNA underwent US\u2010guided ILN excision. Men with \u2265T1G2 local recurrence during follow\u2010up and non\u2010squamous cell histologies were excluded. Descriptive analysis was performed, and sensitivity and negative predictive values (NPVs) were calculated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We included 403 men with 728 groins with negative FNA undergoing DSNB\u2009\u00b1\u2009US\u2010guided LN excision. At least one sentinel LN (SN) was visualised in 93% during the first and in 7% during the second lymphoscintigraphy. The median SNs visualised preoperatively was 1\u2009SN and a median of 2\u2009LNs were resected. ILN metastases were detected in 9% groins in men with impalpable and in 17% men with palpable LNs. Stratified by impalpable and palpable ILN, non\u2010local recurrence despite pathologically negative DSNBs was seen in 0.5% and 0%, respectively. Limited to men with \u226524\u2009months follow\u2010up, non\u2010local recurrence after negative DSNBs was seen in 0.4% and 0%, respectively. The sensitivity of DSNB was 96% and the NPV was 100%. The main limitation of this analysis is its retrospective nature with inherit biases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Inguinal US and FNA followed by DSNB can accurately stage men with both impalpable and palpable ILN, which provides logistical and surgical advantages.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.15700","type":"journal-article","created":{"date-parts":[[2022,1,30]],"date-time":"2022-01-30T02:13:10Z","timestamp":1643508790000},"page":"331-336","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["High diagnostic accuracy of inguinal ultrasonography and fine\u2010needle aspiration followed by dynamic sentinel lymph node biopsy in men with impalpable and palpable inguinal lymph nodes"],"prefix":"10.1111","volume":"130","author":[{"given":"Esther W.C.","family":"Lee","sequence":"first","affiliation":[{"name":"The Christie NHS Foundation Trust  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allaudin","family":"Issa","sequence":"additional","affiliation":[{"name":"The Christie NHS Foundation Trust  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro","family":"Oliveira","sequence":"additional","affiliation":[{"name":"The Christie NHS Foundation Trust  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurice","family":"Lau","sequence":"additional","affiliation":[{"name":"The Christie NHS Foundation Trust  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay","family":"Sangar","sequence":"additional","affiliation":[{"name":"The Christie NHS Foundation Trust  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7733-1057","authenticated-orcid":false,"given":"Arie","family":"Parnham","sequence":"additional","affiliation":[{"name":"The Christie NHS Foundation Trust  Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4073-5488","authenticated-orcid":false,"given":"Christian D.","family":"Fankhauser","sequence":"additional","affiliation":[{"name":"The Christie NHS Foundation Trust  Manchester UK"},{"name":"Luzerner Kantonsspital  Luzern Switzerland"},{"name":"University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,3,5]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ju.0000154565.37397.4d"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2013.06.016"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2013.02.037"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.141.2.183"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euros.2020.12.009"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11255-016-1405-x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2011.09.058"},{"key":"e_1_2_7_9_1","unstructured":"European Association of Urology (EAU)EAU guidelines on penile cancer 2021. 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