{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T17:43:59Z","timestamp":1790963039151,"version":"4.1.0"},"reference-count":23,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,10,3]],"date-time":"2022-10-03T00:00:00Z","timestamp":1664755200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To determine the oncological impact and adverse events of performing simultaneous transurethral resection of bladder tumour (TURB) and transurethral resection of the prostate (TURP), as evidence on the outcomes of simultaneous TURB for bladder cancer and TURP for obstructive benign prostatic hyperplasia is limited and contradictory.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>Patients from 12 European hospitals treated with either TURB alone or simultaneous TURB and TURP (TURB+TURP) were retrospectively analysed. A propensity score matching (PSM) 1:1 was performed with patients from the TURB+TURP group matched to TURB\u2010alone patients. Associations between surgery approach with recurrence\u2010free (RFS) and progression\u2010free (PFS) survivals were assessed in Cox regression models before and after PSM. We performed a subgroup analysis in patients with risk factors for recurrence (multifocality and\/or tumour size &gt;3\u2009cm).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 762 men were included, among whom, 76% (581) underwent a TURB alone and 24% (181) a TURB+TURP. There was no difference in terms of tumour characteristics between the groups. We observed comparable length of stay as well as complication rates including major complications (Clavien\u2013Dindo Grade \u2265III) for the TURB\u2010alone vs TURB+TURP groups, while the latest led to longer operative time (\n                      <jats:italic>P<\/jats:italic>\n                      &lt;\u20090.001). During a median follow\u2010up of 44\u2009months, there were more recurrences in the TURB\u2010alone (47%) compared to the TURB+TURP group (28%;\n                      <jats:italic>P<\/jats:italic>\n                      &lt;\u20090.001). Interestingly, there were more recurrences at the bladder neck\/prostatic fossa in the TURB\u2010alone group (55% vs 3%,\n                      <jats:italic>P<\/jats:italic>\n                      &lt;\u20090.001). TURB+TURP procedures were associated with improved RFS (hazard ratio [HR] 0.39, 95% confidence interval [CI] 0.29\u20130.53;\n                      <jats:italic>P<\/jats:italic>\n                      &lt;\u20090.001), but not PFS (HR 1.63, 95% CI 0.90\u20132.98;\n                      <jats:italic>P<\/jats:italic>\n                      =\u20090.11). Within the PSM cohort of 254 patients, the simultaneous TURB+TURP was still associated with improved RFS (HR 0.33, 95% CI 0.22\u20130.49;\n                      <jats:italic>P<\/jats:italic>\n                      &lt;\u20090.001). This was also true in the subgroup of 380 patients with recurrence risk factors (HR 0.41, 95% CI 0.28\u20130.62;\n                      <jats:italic>P<\/jats:italic>\n                      &lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In our contemporary cohort, simultaneous TURB and TURP seems to be an oncologically safe option that may, even, improve RFS by potentially preventing disease recurrence at the bladder neck and in the prostatic fossa.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.15898","type":"journal-article","created":{"date-parts":[[2022,9,22]],"date-time":"2022-09-22T04:54:40Z","timestamp":1663822480000},"page":"571-580","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Oncological and safety profiles in patients undergoing simultaneous\n                    <scp>transurethral resection (TUR) of bladder tumour<\/scp>\n                    and\n                    <scp>TUR of the prostate<\/scp>"],"prefix":"10.1111","volume":"131","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8953-0272","authenticated-orcid":false,"given":"Ekaterina","family":"Laukhtina","sequence":"first","affiliation":[{"name":"Department of Urology, Comprehensive Cancer Center Medical University of Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3084-2458","authenticated-orcid":false,"given":"Marco","family":"Moschini","sequence":"additional","affiliation":[{"name":"Division of Experimental Oncology\/Unit of Urology Urological Research Institute  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1727-2283","authenticated-orcid":false,"given":"Wojciech","family":"Krajewski","sequence":"additional","affiliation":[{"name":"Department of Minimally Invasive and Robotic Urology, University Center of Excellence in Urology Wroc\u0142aw Medical University  Wroclaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9361-2342","authenticated-orcid":false,"given":"Jeremy Yuen\u2010Chun","family":"Teoh","sequence":"additional","affiliation":[{"name":"Department of Surgery, Prince of Wales Hospital The Chinese University of Hong Kong  Hong Kong China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6004-2152","authenticated-orcid":false,"given":"Guillaume","family":"Ploussard","sequence":"additional","affiliation":[{"name":"Department of Urology, La Croix du Sud Hospital Institut Universitaire du Cancer Toulouse \u2013 Oncopole  Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8443-8453","authenticated-orcid":false,"given":"Francesco","family":"Soria","sequence":"additional","affiliation":[{"name":"Division of Urology, Department of Surgical Sciences, AOU Citt\u00e0 della Salute e della Scienza di Torino Torino School of Medicine  Turin Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0299-489X","authenticated-orcid":false,"given":"Florian","family":"Roghmann","sequence":"additional","affiliation":[{"name":"Department of Urology Marien Hospital Herne  Herne Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mara Anna","family":"Muenker","sequence":"additional","affiliation":[{"name":"Department of Urology Marien Hospital Herne  Herne 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of simultaneous transurethral resection of bladder tumor and transurethral resection of the prostate in comparison with the procedures in two separate sittings in patients with bladder tumor and urodynamically proven bladder outflow obstruction","volume":"184","author":"Singh V","year":"2010","journal-title":"J Urol"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41585-022-00578-1"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2011.10.029"}],"container-title":["BJU 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