{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T06:02:23Z","timestamp":1790402543686,"version":"4.1.0"},"reference-count":30,"publisher":"Wiley","issue":"S3","license":[{"start":{"date-parts":[[2023,7,18]],"date-time":"2023-07-18T00:00:00Z","timestamp":1689638400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2024,2]]},"abstract":"\n Objectives<\/jats:title>\n To assess intrarenal pressures (IRPs) and complication rates after flexible ureteroscopy (fURS), and to assess factors that contribute to raised IRPs and postoperative complications.<\/jats:p>\n <\/jats:sec>\n \n Patients and Methods<\/jats:title>\n After informed consent patients underwent fURS under general anaesthesia. The transducer of a 0.3556\u2009mm (0.014\u2033) pressure guidewire was placed in the renal pelvis for live recording of IRPs. The fURS procedures were performed in a routine manner under antibiotic cover with the aim of dusting the calculus to completion. The operating surgeon was blinded to the live\u2010recorded IRPs.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 40 fURS procedures were performed in 37 patients (26 male and 11 female). The mean age was 50.5\u2009years. As a cohort, the mean of average IRPs was 34.8\u2009mmHg and the mean of maximal IRPs was 128.8\u2009mmHg. Pearson's correlation showed a significant inverse correlation between the mean IRP and age (\n r<\/jats:italic>\n [38]: \u22120.391,\n P<\/jats:italic>\n \u2009=\u20090.013). Three cases experienced postoperative deviations from uncomplicated recovery, with two being hypotensive and one case being both hypotensive and hypoxic. Three cases returned to the emergency department within 30\u2009days of surgery, with two cases of flank pain and one case of urosepsis with positive urine cultures. The patient presenting with urosepsis had exhibited IRPs exceeding the mean.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n The IRPs changed significantly from normal baseline levels during routine fURS. The mean IRP during fURS correlates with patient age, but not with other factors. The IRP may be related to increased complication rates at fURS. Understanding factors that influence IRP will allow urologists to better manage this intraoperatively.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/bju.16113","type":"journal-article","created":{"date-parts":[[2023,7,7]],"date-time":"2023-07-07T07:10:11Z","timestamp":1688713811000},"page":"18-24","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Intrarenal pressures during flexible ureteroscopy: an\u00a0insight into safer endourology"],"prefix":"10.1111","volume":"133","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7786-0605","authenticated-orcid":false,"given":"Anne","family":"Hong","sequence":"first","affiliation":[{"name":"Department of Urology Austin Health Heidelberg Victoria Australia"},{"name":"Faculty of Medicine, Dentistry and Health Sciences University of Melbourne Parkville Victoria 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