{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T23:09:09Z","timestamp":1790982549016,"version":"4.1.0"},"reference-count":64,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,8,8]],"date-time":"2023-08-08T00:00:00Z","timestamp":1691452800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bjui-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["BJU International"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To perform a systematic review and meta\u2010analysis of endoscopic procedures for treating vesico\u2010urethral anastomotic stenosis (VUAS) after prostatectomy, as initial VUAS management remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A search of the MEDLINE database, the Cochrane database, and clinicaltrials.gov was performed (last search February 2023) using the following query: ([\u2018bladder neck\u2019 OR \u2018vesicourethral anastomotic\u2019 OR \u2018anastomotic\u2019] AND [\u2018stricture\u2019 OR \u2018stenosis\u2019 OR \u2018contracture\u2019] AND \u2018prostatectomy\u2019). The primary outcome was the success rate of VUAS treatment, defined by the proportion (%) of patients without VUAS recurrence at the end of follow\u2010up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The literature search identified 420 studies. After the screening, 78 reports were assessed for eligibility, and 40 studies were included in the review. The pooled characteristics of the 40 studies provided a total of 1452 patients, with a median (interquartile range [IQR]) follow\u2010up of 23.7\u2009(13\u201332)\u2009months and age of 66\u2009(64\u201368)\u2009years. The overall success rate (95% confidence interval [CI]) of all endoscopic procedures for VUAS treatment was 72.8%\u2009(64.4%\u201379.9%). Meta\u2010regression models showed a negative influence of radiotherapy on the overall success rate (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009=\u20090.012). After trim\u2010and\u2010fill (addition of 10 studies), the corrected overall success rate (95% CI) was 62.9%\u2009(53.6%\u201371.4%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This first meta\u2010analysis of endoscopic treatment success rate after VUAS reported an overall success rate of 72.8%, lowered to 62.9% after correcting for significant publication bias. This study also highlighted the need for a more thorough reporting of post\u2010prostatectomy VUAS data to understand the treatment pathway and provide higher\u2010quality evidence\u2010based care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/bju.16141","type":"journal-article","created":{"date-parts":[[2023,7,28]],"date-time":"2023-07-28T03:44:57Z","timestamp":1690515897000},"page":"237-245","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Post\u2010prostatectomy anastomotic stenosis: systematic review and meta\u2010analysis of endoscopic treatment"],"prefix":"10.1111","volume":"133","author":[{"given":"Oph\u00e9lie","family":"Delchet","sequence":"first","affiliation":[{"name":"Service d'Urologie, Hospices Civils de Lyon, H\u00f4pital Lyon Sud  Lyon 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